Fig. 3
From: Ferumoxytol-enhanced cardiovascular magnetic resonance detection of early stage acute myocarditis
Detection of myocarditis by FE-CMR, early gadolinium enhancement (EGE), and late gadolinium enhancement (LGE) Representative images of FE-CMR performed at 6 h (6 h-FE-CMR) and 24 h (24 h-FE-CMR) after ferumoxytol administration, EGE, and LGE, are shown (a) (upper row: day 21, middle row: day14, lower row: control). Enhanced areas suggesting inflammation are pointed by arrows. The right panels show inflammatory lesions (both left ventricle (LV) and right ventricle (RV)) segmented on 6 h-FE-CMR in light blue. The box and whisker graph (b) shows the regions detected as myocardial inflammation by 6 h-FE-CMR, 24 h-FE-CMR, EGE, and LGE. At day 14, FE-CMR detected more extensive myocardial inflammation compared with EGE (p = 0.02) and LGE (p < 0.01)