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Table 2 Lesion Characteristics Stratified by 3Di-PMR Cutoff

From: Three-dimensional assessment of coronary high-intensity plaques with T1-weighted cardiovascular magnetic resonance imaging to predict periprocedural myocardial injury after elective percutaneous coronary intervention

 

3Di-PMR < 51 PMR*mm3(n = 84)

3Di-PMR ≥51 PMR*mm3(n = 57)

P Value

Angiographic findings

 Target vessel

  

0.375

 LAD/LCX/RCA

52/14/18

29/9/19

 

 Type B2/C lesion

46 (55)

35 (61)

0.434

 Side branch at the PCI target lesion site

53 (63)

33 (58)

0.534

 Calcification

17 (20)

7 (12)

0.217

 Total lesion length, mm

17 (10–26)

18 (11–28)

0.769

PCI parameters

 Stent diameter, mm

3.0 (2.8–3.3)

3.25 (3.0–3.5)

< 0.001

 Stent length, mm

24 (18–33)

24 (18–37)

0.500

 Post-dilatation balloon size, mm

3.3 (3.0–3.5)

3.5 (3.3–4.0)

< 0.001

Cross-sectional IVUS parameters

(n = 74)

(n = 52)

 

Grayscale IVUS analysis

 Lesion EEM CSA, mm2

8.4 (6.1–11.3)

12.9 (8.9–15.8)

< 0.001

 Lesion lumen CSA, mm2

1.3 (1.0–2.0)

1.3 (0.9–2.0)

0.560

 Lesion P + M CSA, mm2

6.6 (5.0–9.4)

11.3 (8.1–13.5)

< 0.001

 Plaque burden, %

83 (77–86)

89 (85–92)

< 0.001

 Remodeling index

0.89 (0.78–1.05)

1.06 (0.91–1.19)

< 0.001

 Positive remodeling

19 (26)

26 (50)

0.004

 Ultrasound attenuation

6 (8)

18 (35)

< 0.001

 Attenuation length, mm

0 (0–1.7)

3.6 (0–6.6)

< 0.001

 Intracoronary thrombus

2 (3)

9 (18)

0.015

IB-IVUS parameters

 Lipid area, %

68 (57–80)

81 (68–86)

0.003

 Fibrous area, %

24 (17–38)

17 (13–28)

0.007

 Calcified area, %

3.7 (1.1–7.4)

2.0 (0.4–3.7)

0.030

Volumetric IVUS analysis

 Grayscale IVUS parameters

  EEM volume, mm3

174 (135–247)

246 (171–336)

< 0.001

  Lumen volume, mm3

62 (47–93)

75 (57–107)

0.147

  Total plaque volume, mm3

104 (82–140)

158 (114–210)

< 0.001

  Plaque burden, %

61 (55–67)

66 (62–74)

< 0.001

IB-IVUS parameters

 Lipid volume, %

68 (55–78)

71 (63–83)

0.039

 Fibrous volume, %

28 (20–40)

25 (16–33)

0.052

 Calcified volume, %

3.5 (1.6–7.3)

2.4 (0.9–4.0)

0.039

  1. Values are medians (interquartile range) or n (%)
  2. 2D-PMR 2-dimensional plaque-to-myocardium signal intensity ratio, 3Di-PMR 3-dimensional integral of the plaque-to-myocardium signal intensity ratio, CSA Cross-sectional area, EEM External elastic membrane, IB-IVUS Integrated backscatter intravascular ultrasound, LAD Left anterior descending coronary artery, LCX Left circumflex coronary artery, P + M Plaque plus media, PCI Percutaneous coronary intervention, PMR*mm3 the unit of 3Di-PMR; the integral of voxel volume multiplied by its PMR value > 1.0 from a coronary plaque, RCA Right coronary artery
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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