Skip to main content

Table 1 Temperature-adjusted (normalized to 21 °C) native T1 and CoV (%) at 1.5 T summarized by vendor and sequence

From: T1 mapping performance and measurement repeatability: results from the multi-national T1 mapping standardization phantom program (T1MES)

Summary table ofCoV ofT1(%) across 4 tubesOrder of tube IDs follows their orientation in the scanned bottle
SiemensMOLLI 5s(3s)3s [448B]0.27
PhilipsMOLLI 3s(3s)5s0.54
SiemensSASHA0.56
SiemensShMOLLI 5b(1b)1b(1b)1b [1041B]0.64
PhilipsSASHA0.92
PhilipsShMOLLI 5b(1b)1b(1b)1bc1.04
General ElectricMOLLI 5b(1b)1b(1b)1bd1.28
General ElectricSMART3.00
PlatformSequence [prototype, #]’ CoV ofT1(%), global± SD ofT1according to native tube ID [tube rT1 by slow IR]
F [1090 ms]E [1333 ms]D [803 ms]B [1489 ms]
SiemensMOLLI MyoMaps product 5s(3s)3s [5]1.07, 1041 ± 231.38, 1273 ± 350.85, 771 ± 61.45, 1538 ± 46
MOLLI 3b(3s)3b(3s)5b [448, 3]0.87, 1019 ± 111.08, 1225 ± 170.65, 765 ± 61.19, 1462 ± 21
MOLLI 5b(3s)3b [448, 3]0.18, 1005 ± 130.53, 1217 ± 240.26, 762 ± 60.74, 1464 ± 23
MOLLI 5b(3s)3b [448B, 2]0.65, 1052 ± 70.82, 1289 ± 100.61, 784 ± 41.00, 1555 ± 16
MOLLI 5b(3s)3b [780, 2]0.70, 1048 ± 141.18, 1276 ± 200.61, 776 ± 6 sic.1.15, 1536 ± 24
MOLLI 5b(3s)3b [780B, 4]0.76, 1043 ± 90.99, 1279 ± 170.67, 776 ± 61.45, 1550 ± 37
MOLLI 5s(3s)3s [448, 2]0.89, 1035 ± 101.51, 1261 ± 251.04, 770 ± 91.44, 1538 ± 24
MOLLI 5s(3s)3s [448B, 1]a0.14, 1051 ± 10.38, 1282 ± 50.17, 783 ± 10.38, 1553 ± 6
MOLLI 5s(3s)3s [780B, 2]0.81, 1043 ± 150.69, 1277 ± 150.42, 771 ± 60.90, 1546 ± 25
MOLLI 5s(3s)3s [1041, 1]1.11, 1045 ± 120.69, 1285 ± 90.81, 772 ± 60.96, 1560 ± 15
MOLLI 5s(3s)3s [1041B, 1]1.27, 1033 ± 131.80, 1232 ± 220.66, 771 ± 51.47, 1494 ± 22
ShMOLLI 5b(1b)1b(1b)1b [448, 1]1.01, 989 ± 101.39, 1223 ± 170.60, 729 ± 41.50, 1510 ± 23
ShMOLLI 5b(1b)1b(1b)1b [448C, 1]0.61, 983 ± 60.64, 1218 ± 80.63, 727 ± 51.57, 1507 ± 22
ShMOLLI 5b(1b)1b(1b)1b [780B, 3]2.16, 945 ± 343.29, 1147 ± 620.98, 711 ± 113.70, 1392 ± 85
ShMOLLI 5b(1b)1b(1b)1b [1048, 1]0.70, 972 ± 70.71, 1208 ± 90.68, 715 ± 51.01, 1489 ± 15
ShMOLLI 5b(1b)1b(1b)1b [1041B, 1]a0.59, 978 ± 60.67, 1201 ± 80.43, 721 ± 30.86, 1501 ± 13
SASHA [4]0.39, 1104 ± 170.65, 1362 ± 270.47, 814 ± 80.73, 1522 ± 30
PhilipsMOLLI CardiacQuant product 5s(3s)3s [2]0.53, 1025 ± 130.86, 1265 ± 190.50, 760 ± 71.04, 1516 ± 28
MOLLI 3b(3s)3b(3s)5b [2]0.47, 1006 ± 170.94, 1247 ± 390.46, 751 ± 61.25, 1503 ± 46
MOLLI 3s(3s)3s(3s)5s [1]0.94, 1026 ± 101.66, 1251 ± 210.69, 765 ± 52.15, 1450 ± 31
MOLLI 3s(3s)5s [1]a0.20, 936 ± 21.11, 1100 ± 120.27, 722 ± 20.59, 1323 ± 8
MOLLI 5b(3s)3b(3s)2b [1]6.78, 1168 ± 796.32, 1374 ± 873.04, 816 ± 256.53, 1665 ± 109
MOLLI 5b(3s)3b [1]1.18, 1027 ± 121.48, 1265 ± 190.67, 758 ± 51.16, 1522 ± 18
MOLLI 5 s(3s)3s [3]0.89, 1012 ± 171.35, 1233 ± 311.20, 756 ± 91.76, 1456 ± 58
ShMOLLI 5b(1b)1b(1b)1bc [1]0.89, 1027 ± 91.37, 1270 ± 170.50, 753 ± 41.41, 1522 ± 21
SASHA [2]1.02, 1057 ± 440.89, 1336 ± 840.87, 798 ± 300.89, 1505 ± 33
General ElectricMOLLI 5b(3s)5b [1]11.18, 653 ± 737.69, 853 ± 668.45, 591 ± 506.68, 1319 ± 88
MOLLI 5b(1b)1b(1b)1bd [1]a1.40, 575 ± 81.76, 642 ± 110.78, 543 ± 41.19, 1002 ± 12
SMART [1]2.05, 1063 ± 224.76, 1273 ± 610.95, 798 ± 84.22, 1430 ± 60
  1. The term sequence refers to either MOLLI, ShMOLLI, SASHA, or SMART
  2. MOLLI/ShMOLLI protocol nosology has the number of inversions per experiment as the total count of numbers outside brackets, image cycles are outside brackets, pause cycles are within brackets, and cycle lengths defined in terms of either heart beats (b) or seconds (s)
  3. CoV coefficient of variation, ID identity code, GBCA gadolinium-based contrast agent, GE General Electric, MOLLI modified Look-Locker inversion recovery, rT1 “reference” slow inversion recovery T1, SASHA saturation-recovery single-shot acquisition, SD standard deviation, ShMOLLI shortened MOLLI, SMART saturation method using adaptive recovery times for cardiac T1 mapping, T Tesla
  4. aDenotes the T1 mapping sequence|software combination with lowest overall CoV% for a given vendor where multiples exist. P values for differences in CoV between sequences/vendors are reported for this highly repeatable sequence where multiples exist. Less favorable CoVs (> 1%, see the “T1 repeatability” section) are in italics. Post-GBCA tubes are not shown here as their data are reported separately in relation to post-GBCA sequences in Supplementary Table 5
  5. bDenotes the number of different magnets submitting that particular sequence from which the average CoVs were derived
  6. cUsing iterative/data dropping steps in map creation as per ShMOLLI
  7. dIn the absence of iterative/data dropping steps in map creation as per ShMOLLI
  8.  = average CoV across the 4 native tubes for a given sequence
  9. ’ = where more than one sequence type was submitted, individual CoVs were then averaged to derive ’ CoV; while for single sequence submissions x̅’ CoV is from the global mean T1 ± SD for that one sequence