| Alcohol consumption vs. healthy controlsa | Heavy vs. moderate alcohol consumptionb |
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βc | 95% CI | P | βc | 95% CI | P |
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CMR measurements |
Native T1, ms | − 59.19 | −89, −30 | < 0.001 | − 8.83 | −58, 40 | 0.714 |
Post T1, ms | −33.01 | −57, −9 | 0.008 | −21.16 | −51, 8 | 0.155 |
ECV, % | 1.63 | 0.58, 2.67 | 0.003 | 1.29 | −0.25, 2.83 | 0.097 |
PET measurements |
Kmono, min−1 × 10−3 | −10.67 | −21.57, 0.24 | 0.055 | −10.93 | −19.26, −2.61 | 0.012 |
K1, min−1 | −0.04 | −0.17, 0.09 | 0.548 | −0.01 | − 0.12, 0.09 | 0.808 |
- ECV extracellular volume fraction. aThe multivariate model is adjusted for age, BMI, history of smoke, and diastolic blood pressure. bThe multivariate model is adjusted for age, and systolic blood pressure. cValues are the difference in MRI and PET imaging measurements between subjects with moderate to heavy alcohol consumption and healthy controls and between subjects with heavy and moderate alcohol consumption