Fig. 6
Summary of myocyte measurements from histological sections. Data are presented as mean ± SD of measurements in each region for SHAM (n = 4) and TAC (n = 4) groups. a As expected, helix angles from histological sections correlated strongly (R2 = 0.71, p < 0.001) with those from DTI. Grayscale color of markers indicates transmural location (black: ENDO, white: EPI). b A transmural gradient in myocyte fractional anisotropy (MFA) was observed, with lower values in the ENDO than EPI, especially in SHAM myocytes. c Myocyte cross sectional area (CSA) also exhibited a transmural gradient in SHAM hearts, with larger values in the ENDO. In TAC hearts, CSA was elevated, and the transmural gradient was diminished