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Table 1 Baseline clinical characteristics of 33 patients with liver cirrhosis

From: Myocardial structural and functional changes in patients with liver cirrhosis awaiting liver transplantation: a comprehensive cardiovascular magnetic resonance and echocardiographic study

 

All

Child-Pugh class A/B

Child-Pugh class C

P value

N = 33

N = 10

N = 23

Age (years)

56.3 ± 9.9

58.8 ± 7.3

55.3 ± 10.8

0.355

Male (n, %)

25 (75.8%)

9 (90.0%)

16 (69.6%)

0.208

Systolic blood pressure (mmHg)

113.47 ± 14.0

111.5 ± 7.6

114.4 ± 16.2

0.601

Diastolic blood pressure (mmHg)

66.3 ± 12.3

60.9 ± 9.0

68.8 ± 12.9

0.094

Heart rate (/min)

73.6 ± 15.7

63.3 ± 9.1

78.0 ± 16.0

0.002

Cirrhosis etiology (n, %)

   

0.296

 Viral

20 (60.6%)

8 (80.0%)

12 (52.2%)

 

  HBV

17 (51.5%)

6 (60.0%)

11 (47.8%)

 

  HCV

3 (9.1%)

2 (20.0%)

1 (4.3%)

 

 Alcoholic

9 (27.3%)

1 (10.0%)

8 (34.8%)

 

 Autoimmune hepatitis

2 (6.1%)

0 (0%)

2 (8.7%)

 

 Cryptogenic

2 (6.1%)

1 (10.0%)

1 (4.3%)

 

 Child-Pugh score

9.8 ± 2.4

6.8 ± 1.3

11.1 ± 1.2

< 0.001

 MELD score

18.8 ± 7.4

11.1 ± 2.1

22.1 ± 6.3

< 0.001

Underlying diseases (n, %)

 Hypertension

8 (24.2%)

4 (40.0%)

4 (17.4%)

0.164

 Diabetes mellitus

9 (27.3%)

4 (40.0%)

5 (21.7%)

0.279

Medication (n, %)

 Beta-blockers

8 (24.2%)

6 (60.0%)

2 (8.7%)

0.002

 Diuretics

17 (51.5%)

4 (40.0%)

13 (56.5%)

0.383

 ACEI/ARB

3 (9.1%)

2 (20%)

1 (4.3%)

0.151

Laboratory examination

 Hemoglobin (g/dL)

10.6 ± 1.6

11.4 ± 1.6

10.2 ± 1.5

0.050

 Creatinine (mg/dL)

0.9 ± 0.4

0.8 ± 0.2

0.9 ± 0.4

0.565

 Bilirubin (mg/dL)

7.5 ± 8.5

1.7 ± 0.6

10.0 ± 9.1

< 0.001

 Albumin (g/dL)

2.9 ± 0.4

3.2 ± 0.4

2.7 ± 0.4

0.002

 PT (INR)

1.9 ± 1.0

1.3 ± 0.2

2.1 ± 1.1

0.001

  1. Values are shown as number (%) or mean ± standard deviation
  2. HBV hepatitis B virus, HCV hepatitis C virus, MELD the model for end stage liver disease, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin II receptor blockers, PT prothrombin time, INR international normalized ratio