Skip to main content

Table 2 Baseline echocardiographic and electrocardiographic parameters

From: Myocardial structural and functional changes in patients with liver cirrhosis awaiting liver transplantation: a comprehensive cardiovascular magnetic resonance and echocardiographic study

 Healthy controlsCirrhosisChild-Pugh class A/BChild-Pugh class CP valueP value*
N = 17N = 33N = 10N = 23
LVEF (%)62.7 ± 5.666.0 ± 5.266.4 ± 3.565.8 ± 5.80.0490.777
LV EDD (mm)47.9 ± 4.048.0 ± 5.548.6 ± 4.847.7 ± 5.90.9690.686
LV ESD (mm)29.7 ± 4.328.0 ± 4.328.2 ± 3.428.0 ± 4.70.2060.905
LV wall thickness (mm)9.1 ± 0.98.9 ± 1.39.2 ± 1.38.8 ± 1.30.7470.456
E/A ratio0.9 ± 0.41.1 ± 0.41.1 ± 0.41.2 ± 0.50.1650.431
Deceleration time (msec)210.2 ± 30.2212.3 ± 41.0232.3 ± 39.6203.2 ± 39.10.8570.061
E/e’ ratio8.6 ± 2.510.4 ± 2.510.8 ± 2.410.2 ± 2.50.0180.431
Diastolic function    0.4740.776
 Normal9 (52.9%)17 (51.5%)5 (50.0%)12 (52.2%)  
 Indeterminate7 (41.2%)15 (45.5%)5 (50.0%)10 (43.5%)  
 Grade 11 (5.9%)0 (0%)    
 Grade 20 (0%)1 (3.0%)0 (0%)1 (4.3%)  
LA dimension (mm)38.2 ± 3.843.7 ± 7.747.1 ± 8.942.2 ± 6.70.0080.094
LAVI (mL/m2)39.8 ± 7.847.3 ± 11.245.6 ± 12.048.0 ± 11.00.0200.565
Estimated PASP (mmHg)32.1 ± 3.133.8 ± 5.331.0 ± 2.935.1 ± 5.70.3480.040
GLS (%)−18.6 ± 2.2−24.2 ± 2.7−25.2 ± 2.7−23.8 ± 2.6< 0.0010.170
GCS (%)−26.1 ± 4.7−27.8 ± 5.1−27.7 ± 5.1−27.8 ± 5.20.2540.950
Positive agitated saline test (n, %)0 (0%)22 (66.7%)6 (60.0%)16 (69.6%)0.592
QTc interval (msec)410.5 ± 8.6470.3 ± 36.1453.7 ± 19.9477.6 ± 39.4< 0.0010.081
  1. LVEF left ventricular ejection fraction, EDD end-diastolic diameter, ESD end-systolic diameter, E peak early diastolic mitral inflow velocity, A peak late diastolic transmitral peak velocity, e’ early diastolic mitral annular velocity, LA left atrium, LAVI left atrial volume index, PASP pulmonary artery systolic pressure, GLS global longitudinal strain, GCS global circumferential strain, QTc corrected QT interval
  2. P value between normal and all liver cirrhosis groups
  3. *P value between Child-Pugh class A/B and Child-Pugh class C