Myocardial structural and functional changes in patients with liver cirrhosis awaiting liver transplantation: a comprehensive cardiovascular magnetic resonance and echocardiographic study

Table 3 Baseline cardiovascular magnetic resonance parameters

	Healthy controls	Cirrhosis	Child-Pugh class A/B	Child-Pugh class C	P value^†	P value^*
	N = 20	N = 33	N = 10	N = 23	P value^†	P value^*
LVEF (%)	63.4 ± 6.4	67.8 ± 6.9	66.1 ± 6.5	68.5 ± 7.1	0.027	0.368
LV EDV (mL)	135 ± 20	150 ± 47	153 ± 42	149 ± 50	0.101	0.811
LV ESV (mL)	51 ± 16	49 ± 21	52 ± 18	48 ± 23	0.752	0.604
Stroke volume (mL)	85 ± 15	100 ± 29	101 ± 28	99 ± 30	0.025	0.845
Cardiac index (L/min)	3.3 ± 0.7	4.3 ± 1.1	3.8 ± 1.0	4.5 ± 1.1	0.002	0.073
LV mass index (g/m²)	76.8 ± 13.0	70.7 ± 15.8	70.1 ± 13.0	71.0 ± 17.1	0.138	0.858
LV mass/LV-EDV ratio	0.9 ± 0.2	0.8 ± 0.3	0.8 ± 0.3	0.9 ± 0.2	0.126	0.875
Presence of LGE	0 (0%)	1 (3.0%)	0 (0%)	1 (4.3%)	0.432	0.503
Native T1 (msec)	1174 ± 65	1228 ± 79	1216 ± 60	1233 ± 87	0.001	0.584
ECV (%)	25.4 ± 1.9	31.6 ± 5.1	27.2 ± 3.4	33.6 ± 4.4	< 0.001	0.001

LVEF left ventricular ejection fraction, EDV end-diastolic volume, ESV end-systolic volume, LGE late gadolinium enhancement, ECV extracellular volume fraction
^†P value between normal and all LC groups
^*P value between Child-Pugh class A/B and Child-Pugh class C

ISSN: 1532-429X