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Table 3 Features and findings of treadmill exercise Cardiac MRI studies in coronary artery disease

From: Exercise cardiovascular magnetic resonance: development, current utility and future applications

Study

Patient population

n.

Mean

Age

(years)

Treadmill location

Findings

Rerkpattanapipat

(2003) [33]

Patients referred for coronary angiography

27

62 ± 11

Outside scanner room

Detected coronary artery stenosis > 70% on coronary angiography with sensitivity and specificity of 79% & 85%.

Raman (2010) [31]

Patients referred for SPECT

43

54 ± 12

MR scanner room corner

Exercise stress CMR is feasible with cine wall motion and perfusion assessment and has moderate agreement with SPECT (K = 0.58)

Sukpraphrute (2015) [43]

Patients with known or suspected CAD

115

59 ± 13

Outside scanner room

Treadmill Ex-CMR RWMA assessment identified those at risk of future adverse events (myocardial infarction, death, unstable angina prompting admission) 47% with RWMA vs 17% without

Raman (EXACT trial)

(2016) [45]

Patients referred for SPECT

94

59 ± 13

Scanner adjacent

Treadmill stress CMR demonstrated a stronger correlation with coronary angiography and superior specificity, sensitivity, positive and negative predictive values for > 70% stenosis at angiography than treadmill SPECT

  1. Abbreviations: CAD coronary artery disease, CMR cardiovascular magnetic resonance, RWMA regional wall motion abnormality, SPECT single photon emission computed tomography,