Fig. 1

Individual cardiac hemodynamic response to exercise in pediatric cancer survivors with normal or impaired cardiopulmonary fitness. Survivors with impaired fitness had a blunted increase in cardiac index (CI) compared to survivors with normal fitness (Fig. 1a). Stroke volume index (SVI) was lower in the impaired fitness group, with minimal augmentation from rest to peak exercise (Fig. 1b), whilst the heart rate response was similar (Fig. 1c)