Exercise cardiovascular magnetic resonance reveals reduced cardiac reserve in pediatric cancer survivors with impaired cardiopulmonary fitness

Table 2 Exercise capacity and cardiopulmonary parameters

	Normal Fitness	Impaired Fitness	P
Cardiopulmonary Exercise Testing
% Predicted HR_max (%)	99 ± 7	98 ± 5	0.65
Respiratory exchange ratio	1.20 ± 0.07	1.33 ± 0.20	0.086
Peak Workload (watts)	234 ± 89	156 ± 85	0.089
Exercise Time (mins)	9.0 (6.0, 12.0)	8.5 (5.3–11.8)	0.22
Peak VO₂ (L/min)	2.5 ± 1.1	1.5 ± 0.7	0.018
Peak VO₂ (mL/kg/min)	40.8 ± 10.0	27.3 ± 7.4	0.003
% Predicted Peak VO₂ (%)	97 ± 14	70 ± 16	0.001
VO₂ at AT (L/min)	1.7 ± 0.7	1.1 ± 0.4	0.025
% Predicted Peak VO₂ at AT (%)	66 ± 12	50 ± 14	0.02

Values are mean ± SD or median (interquartile range). Abbreviations: AT Anaerobic threshold, HR Heart rate, RER Respiratory exchange ratio

ISSN: 1532-429X