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Table 3 Resting and peak cardiac function

From: Exercise cardiovascular magnetic resonance reveals reduced cardiac reserve in pediatric cancer survivors with impaired cardiopulmonary fitness

 

Normal Fitness

Impaired Fitness

P

Resting Echocardiography

 LVEF, %

55.1 ± 3.6

55.3 ± 8.6

0.97

 LV FS, %

32.9 ± 5.4

30.5 ± 5.0

0.32

 GLS, %

−18.6 ± 2.4

− 17.8 ± 2.1 a

0.46

 E/A

1.87 (1.09, 2.65)

1.79 (0.77, 2.81)

0.79

 E/e’

6.0 (4.4, 7.6)

6.8 (5.1, 8.5)

0.26

 DT, cm/s

183 ± 23

176 ± 64

0.64

Resting CMR

 GLS, %

−15.3 ± 2.3

−14.9 ± 2.0 b

0.69

 LVEF, %

53.8 ± 3.8

52.6 ± 6.6

0.66

 RVEF, %

49.4 ± 4.0

55.6 ± 4.8

0.006

 SVI, mL/m2

51 ± 11

43 ± 9

0.09

 CI, L/min/m2

4.0 ± 1.0

3.6 ± 0.6

0.29

Exercise CMR

 LVEFpeak, %

65.0 ± 3.2

60.0 ± 7.8

0.07

 RVEFpeak, %

62.8 ± 5.1

63.9 ± 6.3

0.67

 SVIpeak, mL/m2

60 ± 15

44 ± 9

0.007

 CIpeak, L/min/m2

9.0 ± 1.6

6.8 ± 1.2

0.003

 a-vO2 diffc

16.3 ± 3.3

12.9 ± 2.5

0.016

  1. Values are means ±SD or median (interquartile range). LV Left ventricular, LVEF Left ventricular ejection fraction, FS Fractional shortening, GLS Global longitudinal strain, E/A Ratio of peak early-to-late mitral inflow velocities, E/e’ Ratio of peak mitral inflow to peak early mitral annular velocity, DT Deceleration time, CMR Cardiovascular magnetic resonance imaging, RVEF Right ventricular ejection fraction, SVI Stroke volume index, CI Cardiac index, a-vO2 diff Arterio-venous oxygen difference. a n = 7; b n = 11; c calculated using peak VO2 from cardiopulmonary exercise test and peak cardiac output from exercise CMR
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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