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Table 2 Magnitude of flow change with and without offset correction

From: The clinical impact of phase offset errors and different correction methods in cardiovascular magnetic resonance phase contrast imaging: a multi-scanner study

 

No correction

Optimized ST correction

1st order correction

2nd order correction

3rd order correction

P-value῀

no vs. opt.

P-value ‡

no vs. 1st

P-value

no vs. 2nd

P-value $

no vs 3rd

Medis QFlow

 Net flow (ml/m2)a

48 ± 13

47 ± 13

 Velocity offset (cm/s)

0.0 ± 2.0

− 0.5 ± 1.8

< 0.001

 Absolute velocity offset (cm/s)

1.0 ± 1.7

1.3 ± 1.2

< 0.001

 Difference in net flow with phantom correction (%)b

  Difference

0.2 ± 15.4

−3.2 ± 12.8

< 0.001

  Absolute difference

3.3 (1.2 to 7.3)

6.1 (3.0 to 11.2)

< 0.001

  Range of difference

− 78 to 155

−66 to 74

 Clinically significant differences (> 10%)

65 (19%)

103 (30%)

< 0.001

MASS

 Net flow (ml/m2)a

48 ± 13

48 ± 12

47 ± 13

49 ± 13

48 ± 12

 Velocity offset (cm/s)

0.1 ± 2.0

0.0 ± 1.5

−0.3 ± 1.8

0.3 ± 1.6

0.3 ± 1.6

0.247

< 0.001

0.082

0.276

 Absolute velocity offset (cm/s)

1.0 ± 1.7

0.9 ± 1.2

1.3 ± 1.3

1.1 ± 1.2

1.1 ± 1.1

0.418

< 0.001

0.013

0.003

 Difference in net flow with phantom correction (%)b

  Difference

0.8 ± 15.6

−0.1 ± 11.1

−2.0 ± 13.0

2.7 ± 13.4

1.8 ± 12.2

0.379

< 0.001

0.060

0.281

  Absolute difference

3.2 (1.3 to 7.2)

3.7 (1.5 to 8.5)

5.6 (2.4 to 10.4)

4.3 (1.6 to 9.3)

4.6 (2.2 to 9.2)

0.342

< 0.001

0.015

0.004

  Range of difference

−78 to 161

−35 to 101

−65 to 69

−58 to 101

− 37 to 120

 Clinically significant differences (> 10%)

62 (18%)

67 (19%)

93 (27%)

74 (21%)

79 (23%)

< 0.001

< 0.001

< 0.001

< 0.001

Circle cvi42

 Net flow (ml/m2)a

47 ± 13

47 ± 13

45 ± 12

47 ± 13

47 ± 13

 Velocity offset (cm/s)

0.0 ± 2.2

−0.2 ± 2.0

− 0.7 ± 2.2

− 0.1 ± 2.1

− 0.1 ± 2.2

0.063

< 0.001

0.607

0.566

 Absolute velocity offset (cm/s)

1.2 ± 1.9

1.4 ± 1.5

1.7 ± 1.6

1.4 ± 1.6

1.5 ± 1.6

0.006

< 0.001

0.014

< 0.001

 Difference in net flow with phantom correction (%)b

  Difference

0.0 ± 16.0

−1.8 ± 14.3

−4.8 ± 15.0

− 0.5 ± 15.2

−0.7 ± 15.5

0.046

< 0.001

0.640

0.563

  Absolute difference

4.1 (1.4 to 9.2)

6.0 (2.2 to 11.9)

8.0 (4.3 to 13.6)

5.3 (2.2 to 12.1)

6.1 (2.2 to 13.2)

0.005

< 0.001

0.011

< 0.001

  Range of difference

−93 to 131

−62 to 59

−66 to 59

− 85 to 71

−80 to 75

 Clinically significant differences (> 10%)

80 (23%)

103 (30%)

137 (40%)

107 (31%)

115 (33%)

< 0.001

< 0.001

< 0.001

< 0.001

  1. Values are presented as mean ± standard deviation, median (interquartile range), range minimum to maximum or number (percentage)
  2. Opt. Optimized stationary tissue (ST) correction
  3. p-values no correction versus optimized ST correction, ‡ p-values no correction versus first order correction, p-values no correction versus second order correction, $ p-values no correction versus third order correction
  4. a Indicates net flow per heartbeat, with phantom correction the mean net flow was 48 ± 11 ml/ m2 in all software packages, b Minus indicates flow was lower compared to phantom flow measurements