Table 1 Clinical, laboratory and cardiovascular magnetic resonance (CMR) parameters for the baseline, dehydration and hydration scan
Variable | Baseline scan (n = 12) | Dehydration scan (n = 12) | Hydration scan (n = 12) | P value |
|---|---|---|---|---|
Clinical parameters | ||||
Systolic blood pressure (mmHg) | 124 ± 12 | 122 ± 10 | 122 ± 9 | 0.520 |
Diastolic blood pressure (mmHg) | 69 ± 7 | 72 ± 9 | 67 ± 7 | 0.212 |
Heart rate (bpm) | 63 ± 6§ | 59 ± 11* | 64 ± 10 | 0.014 |
Laboratory parameters | ||||
Sodium (mmol/l) | 140 ± 2 | 141 ± 3 | 140 ± 3 | 0.210 |
Potassium(mmol/l) | 4.3 ± 0.5 | 4.1 ± 0.4 | 4.0 ± 0.5 | 0.125 |
Calcium (mmol/l) | 2.4 ± 0.1 | 2.4 ± 0.1 | 2.4 ± 0.1 | 0.175 |
Chloride (mmol/l) | 102 ± 2 | 102 ± 3 | 101 ± 3 | 0.147 |
Magnesium (mmol/l) | 0.8 ± 0.1§ | 0.9 ± 0.1*‡ | 0.8 ± 0.1§ | 0.002 |
Creatinine (mg/dl) | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.226 |
White blood cell count (G/l) | 5.8 ± 0.7§ | 7.4 ± 2.0* | 6.9 ± 1.4 | 0.003 |
Red blood cell count (G/l) | 5.0 ± 0.4 | 5.1 ± 0.5‡ | 5.0 ± 0.5§ | 0.021 |
Hemoglobin (g/dl) | 14.5 ± 1.1 | 14.7 ± 1.1 | 14.5 ± 1.2 | 0.184 |
Hematocrit (%) | 41.8 ± 3.0 | 43.0 ± 3.6‡ | 41.7 ± 3.8§ | 0.021 |
Platelet count (G/l) | 238 ± 43§ | 255 ± 56*‡ | 241 ± 50§ | 0.009 |
Cardiac MRI parameters | ||||
Left ventricular ejection fraction (%) | 64.8 ± 3.8 | 62.3 ± 3.7 | 66.9 ± 4.5 | 0.179 |
Left ventricular end-diastolic volume (ml) | 141.3 ± 28.7 | 142.9 ± 35.7 | 149.2 ± 35.7 | 0.076 |
Left ventricular end-diastolic volume index (ml/m2) | 78.5 ± 13.1 | 76.2 ± 12.8§ | 80.3 ± 12.9‡ | 0.009 |
End-diastolic wall mass (g) | 82.3 ± 20.2 | 80.2 ± 24.3 | 88.91 ± 26.2 | 0.010 |
Right ventricular ejection fraction (%) | 63.0 ± 6.4 | 59.5 ± 5.9 | 62.4 ± 7.6 | 0.420 |
Right ventricular end-diastolic volume (ml) | 151.2 ± 36.7 | 144.9 ± 36.4 | 148.8 ± 38.0 | 0.558 |
Right ventricular end-diastolic volume index (ml/m2) | 81.5 ± 14.5 | 78.0 ± 14.2 | 80.2 ± 15.3 | 0.558 |
Native T1 relaxation time (ms) | 987 ± 27‡ | 968 ± 29*§ | 986 ± 28‡ | 0.006 |
T2 relaxation time (ms) | 52.9 ± 1.8 | 51.5 ± 2.1 | 52.2 ± 1.9 | 0.020 |