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Table 4 Cox proportional hazard regression analysis for the outcome of 5-year all-cause mortality

From: Layer-specific strain in patients with heart failure using cardiovascular magnetic resonance: not all layers are the same

 

Patients with HF or at risk for HF- 376 subjects (33 events)

Univariable analysis

Multivariable analysis

HR (95% CI)

p-value

Model χ2

HR (95% CI)

p-value

Age at CMR, per 10 year increase

2.37 (1.58,3.56)

 < 0.001

21.5

  

Male gender

0.66 (0.32,1.34)

0.25

1.4

  

BMI, per 1 kg/m2 increase

1.00 (0.94,1.06)

0.99

0.1

  

Systolic blood pressure, per 10 mmHg increase

0.80 (0.66,0.98)

0.031

0.2

  

Current smoker

1.34 (0.93,1.91)

0.12

2.6

  

History of heart failure

6.43 (1.96,21.08)

0.002

15.3

  

Hypertension

1.07 (0.48,2.38)

0.86

0.1

  

Coronary artery disease

2.15 (1.11,4.17)

0.023

5.1

  

Atrial fibrillation/flutter

2.81 (1.42,5.58)

0.003

8.6

  

Diabetes

0.81 (0.39,1.70)

0.58

0.3

  

COPD

1.92 (0.87,4.26)

0.11

2.3

  

Chronic kidney disease

1.20 (0.50,2.91)

0.69

0.2

  

Log (NT-proBNP), per 1 unit increase

1.84 (1.44,2.36)

 < 0.001

27.5

  

Log (Creatinine), per 1 unit increase

3.20 (1.37,7.49)

0.007

6.2

  

LVEF, per 10% decrease

1.37 (1.10,1.71)

0.004

7.6

1.22 (0.95,1.58)

0.12

LVEDVI, per 10 ml/m2 increase

1.09 (1.00,1.18)

0.043

3.5

1.06 (0.97,1.15)

0.19

LVESVI, per 10 ml/m2 increase

1.11 (1.02,1.20)

0.013

5.0

1.07 (0.97,1.17)

0.16

LVM index, per 10 g/m2 increase

1.14 (1.00,1.29)

0.051

3.3

1.09 (0.95,1.25)

0.25

LVM/LVEDV, per 0.1 increase

0.98 (0.82,1.17)

0.82

0.1

0.92 (0.81,1.03)

0.14

GLS_EPI, per 1% absolute decrease

1.11 (1.04,1.18)

0.002

9.4

1.09 (0.98,1.22)

0.11

GLS_AVE, per 1% absolute decrease

1.14 (1.06,1.23)

 < 0.001

12.5

1.10 (1.01,1.20)

0.023

GLS_ENDO, per 1% absolute decrease

1.10 (1.04, 1.18)

0.002

9.2

LR chi2 (2) = 1

LR chi2 (2) = 1

1.06 (0.98, 1.15)

0.15

GCS_EPI, per 1% absolute decrease

1.01 (0.91,1.13)

0.83

0.1

0.99 (0.90,1.10)

0.87

GCS_AVE, per 1% absolute decrease

1.05 (0.99, 1.12)

0.10

2.6

1.02 (0.95,1.09)

0.57

GCS_ENDO, per 1% absolute decrease

1.04 (1.00,1.08)

0.044

4.0

1.02 (0.98,1.06)

0.41

GRS_LAx, per 1% decrease

1.03 (1.01,1.05)

0.001

12.2

1.03 (1.00,1.05)

0.024

GRS_SAx, per 1% decrease

1.03 (1.01,1.05)

0.002

11.9

1.03 (1.00,1.05)

0.019

  1. Base model: age + log (NT-proBNP)
  2. See Tables 1, 2 for abbreviations
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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