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Table 4 Pre- and Post-AVR parameters in patients with and without restored CircE post-AVR

From: Circulatory efficiency in patients with severe aortic valve stenosis before and after aortic valve replacement

 

Pre-AVR not restored CircE (n = 10)

Post-AVR not restored CircE (n = 10)

Pre-AVR restored CircE (n = 31)

Post-AVR restored CircE (n = 31)

Power and efficiency

 LV myocardial power/BSA [W/m2]

9.5 ± 3.3

6.9 ± 2.0*+

7.5 ± 2.6

4.7 ± 1.5*

 Circulatory power [W]

1.3 ± 0.4

1.1 ± 0.4

1.3 ± 0.4

1.3 ± 0.4

 Circulatory efficiency [%]

7.8 ± 3.2

8.5 ± 0.9+

9.7 ± 3.2

14.9 ± 5.1*

 Circulatory efficiency improvement [%]

–

0.6 ± 2.8+

–

5.2 ± 6.0

Conventional parameters of cardiac vascular function

 Myocardial mass/BSA [mg/m2]

75 ± 23

53 ± 13*

71 ± 21

49 ± 13*

 Myocardial wall thickness end systolic [mm]

11 ± 2

10 ± 1*

11 ± 2

10 ± 2*

 LVEDV/BSA [ml/m2]

99 ± 24

78 ± 14*

92 ± 21

77 ± 13*

 LVESV/BSA [ml/m2]

52 ± 27

34 ± 11*

37 ± 13

30 ± 8*

 Mass-volume-index [g/ml]

0.8 ± 0.1

0.7 ± 0.1*

0.8 ± 0.2

0.7 ± 0.2*

 LVESD [mm]

38 ± 7

33 ± 4*

33 ± 5

31 ± 4*

 Left atrium [cm2]

50 ± 15

43 ± 11

48 ± 17

47 ± 15

 LVP [mmHg]

224 ± 21

164 ± 23*

219 ± 26

154 ± 20*

 Heart rate [bpm]

68 ± 11

67 ± 10

66 ± 11

70 ± 12

 CO_total [l/min]

6.4 ± 1.4

5.8 ± 1.2

7.0 ± 2.0

6.5 ± 1.8

 CI [(l/min)/m2]

3.2 ± 0.7

3.0 ± 0.5

3.6 ± 0.8

3.3 ± 0.8

 SV_total [ml]

73 ± 18

73 ± 14

81 ± 20

77 ± 15

 ECV midwall [%]

24 ± 2

28 ± 5

23 ± 2

27 ± 3*

 aECV midwall [ml]

32 ± 13

28 ± 10

32 ± 11

26 ± 8*

 aECV/BSA midwall [ml/m2]

17 ± 7

15 ± 5

16 ± 5

13 ± 3*

 GLS [%]

− 20 ± 6

− 24 ± 4*

− 22 ± 5

− 25 ± 4*

 LVEF [%]

50 ± 13+

57 ± 7*

60 ± 8

62 ± 6

 LGE, n(%)

2 (20%)

2 (20%)

3 (10%)

6 (19%)

Metabolic parameters

 NT-pro-BNP [ng/l]

1356 ± 1570

346 ± 260*

559 ± 427

329 ± 266*

 Hemoglobin [g/dl]

14.7 ± 1.0

13.3 ± 1.0*

14.0 ± 1.4

13.6 ± 1.3*

 Hematocrit [%]

43 ± 3

42.4 ± 3.1

41 ± 4

41.9 ± 3.8

Clinical parameters

 Mean aortic pressure gradient [mmHg]

58 ± 14

15 ± 5*+

56 ± 16

10 ± 5*

 Systolic blood pressure [mmHg]

140 ± 12

142 ± 21

137 ± 19

136 ± 19

 Diastolic blood pressure [mmHg]

80 ± 6+

74 ± 8

73 ± 11

75 ± 9

 Pulse pressure [mmHg]

60 ± 14

68 ± 17

63 ± 17

61 ± 15

 NYHA III-IV, n [%]

5 (50%)

1 (10%)

13 (42%)

2 (6%)*

 6-min walk distance [m]

–

540 ± 32

–

511 ± 93

  1. LVESD, left ventricular end systolic diameter; EDV, end diastolic volume; ESV, end systolic volume; LA, left atrium; HR, heart rate; CO, cardiac output; CI, cardiac index; SV, stroke volume; LVP, left ventricular pressure; NYHA, New York Heart Association; NT-pro-BNP, N terminales pro brain natriuretic peptide; ECV, extracellular volume; aECV, absolute extracellular volume; GLS, global longitudinal strain; EF, ejection fraction;
  2. *p < 0.05 not restored CircE pre-AVR vs not restored CircE post-AVR or restored CircE pre-AVR vs restored CircE post-AVR
  3.  + p < 0.05 not restored CircE pre-AVR vs restored CircE pre-AVR or not restored CircE post-AVR vs restored CircE post-AVR
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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