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Table 2 Metrics of left ventricular function from standard CMR

From: T1-Mapping and extracellular volume estimates in pediatric subjects with Duchenne muscular dystrophy and healthy controls at 3T

 

Healthy Control

N = 20

DMD

N = 28

p-Value

DMD LGE−

N = 17

p-value

DMD LGE + 

N =9

p-Value

LVEF (%)

55.9 (5.8)

49.5 (11.3)

0.003

55.2 (10.9)#

0.20

44.8 (10.7)

 < 0.001

LVEDVI (ml/m2)

87.7 (15.2)

82.8 (27.9)

0.10

68.2 (26.8)#

0.02

91.8 (39.6)

0.81

LVESVI (ml/m2)

38.5 (8.5)

38.7 (14.5)

0.89

36.4 (9.7)#

0.02

45.5 (28.7)

0.03

LVMI (g/m2)

38.4 (7.8)

35.6 (9.8)

0.04

32.4 (8.4)

0.02

39.5 (8.7)

0.94

  1. All subgroups compared to healthy controls. p-value ≤ 0.05 is significant
  2. LVEF, left ventricular ejection fraction; LVEDVI left ventricular end-diastolic volume; LVESVI left ventricular end-systolic volume; LVMI left ventricular mass index; LGE-, late gadolinium enhancement negative; LGE+, late gadolinium enhancement positive
  3. #p ≤ 0.05 comparison between LGE − and LGE + boys