Fig. 7

Acute and chronic post-ablation imaging for evaluating long term lesion size. The enhancing boundaries for RF ablation lesions (green), and chemoablation (orange) are well visualized by (a) acute native contrast T1w imaging (Day 0), and (b) chronic late gadolinium enhancement (LGE) on Day 21. Both show excellent correspondence to ex vivo LGE (c,e,f) and trichrome stain histology (g,h) performed on Day 21. These results support the hypothesis that T1w imaging on the day of ablation describes long-term lesion size. Histology shows that encapsulation and the wavefront of healing progress inwards as collagen and scar tissue (s, light blue) replace resorbed necrosis