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Table 1 Baseline characteristics and comparison of PET results of patients with positive vs negative splenic switch off

From: Splenic switch-off as a predictor for coronary adenosine response: validation against 13N-ammonia during co-injection myocardial perfusion imaging on a hybrid PET/CMR scanner

 

All patients

n = 64

SSO present

n = 46 (72%)

SSO absent

n = 18 (28%)

p-Value

Baseline characteristics

Mean age (years)

51 ± 20

51.4 ± 18

49.2 ±24 

0.69

Male gender

52 (81)

37 (80)

15 (83)

0.30

Weight (kg)

80 ± 11

81 ± 10

75 ± 12

0.047

Height (cm)

175 ± 8

175 ± 8

176 (± 8

0.65

Body mass index(kg/m2)

26 ± 3

27 ± 3

24 ± 3

0.006

Risk factors

Diabetes mellitus

5 (7.8)

5 (11)

0 (0)

0.145

Dyslipidaemia

27 (42)

21 (46)

6 (34)

0.37

Hypertension

25 (39)

20 (43)

5 (28)

0.247

Family history

16 (25)

12 (26)

4 (23)

0.748

Smoking

21 (33)

17 (37)

4 (23)

0.259

Medication

Aspirin

24 (38)

17 (37)

7(39)

0.886

Betablocker

18 (28)

15 (33)

3 (17)

0.202

ACE inhibitor

24 (38)

18 (39)

6 (34)

0.667

Statin

27 (42)

19 (41)

8 (45)

0.819

Medical history

Myocardial infarction

10 (16)

7 (15)

3 (17)

0.886

Stenting

18 (28)

13 (28)

5 (28)

0.969

CABG

7 (11)

4 (9)

3 (170)

0.358

13N-ammonia PET

Ischemia

15 (23)

9 (20)

6 (34)

0.242

Scar

33 (52)

22 (48)

11 (61)

0.1

Stress MBF (ml/min/g)

2.12 ± 0.68

2.2 ± 0.66

1.93 ± 0.72

0.23

Rest MBF (ml/min/g)

0.78 ± 0.26

0.77 ± 0.27

0.81 ± 0.24

0.65

MFR

2.91 (± 1)

3.07 ± 1.03

2.48 ± 0.96

0.038

  1. Values given are average ± standard deviations or absolute numbers and percentages (in brackets)
  2. ACE  angiotensin converting enzyme, CABG  coronary artery bypass graft, CAD  coronary artery disease, MBF  myocardial blood flow, MFR  myocardial flow reserve. SSO  splenic switch-off