Table 3 Associations of trajectory clusters for individual CVD risk factors (representing low, medium and high cumulative exposure to this risk factor over 14 years) with CMR derived measures of cardiac structure and function

Systolic BP (low)

101

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 (middle)

149

0.03 (− 4.13; 4.19)

1.00 (− 1.58; 3.57)

2.13 (− 1.32; 5.58)

− 18.47 (− 48.99; 12.04)

− 0.26 (− 4.9; 4.37)

0.97 (− 1.56; 3.5)

− 0.40 (− 1.44; 0.65)

− 2.68 (− 6.10; 0.75)

 (high)

99

3.23 (− 2.48; 8.93)

2.46(− 1.07; 6.00)

7.42** (2.69; 12.16)

− 31.73 (− 73.58; 10.13)

1.73 (− 4.72; 8.19)

2.12 (− 1.40; 5.64)

0.02 (− 1.41; 1.45)

0.09 (− 4.58; 4.76)

Diastolic BP (low)

135

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 (middle)

142

− 2.76 (− 6.83; 1.3)

− 1.42 (− 3.93; 1.08)

− 1.29 (− 4.64; 2.05)

− 24.42 (− 54.13; 5.29)

− 2.01 (− 6.55; 2.52)

− 1.06 (− 3.53; 1.40)

0.11 (− 0.90; 1.11)

− 0.80 (− 4.13; 2.52)

 (high)

72

− 4.63 (− 10.32; 1.06)

− 4.61* (− 8.12; − 1.10)

− 2.53 (− 7.21; 2.16)

− 54.49* (− 96.09; − 12.89)

− 5.77 (− 12.05; 0.51)

− 4.31* (− 7.72; − 0.90)

2.12** (0.71; 3.52)

5.02* (0.39; 9.65)

Waist circumference (low)

97

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 (middle)

180

− 4.31* (− 8.53; − 0.09)

− 3.18* (− 5.79; − 0.56)

2.23 (− 1.18; 5.65)

− 10.68 (− 41.49; 20.12)

− 6.59** (− 11.39; − 1.79)

− 3.05* (− 5.66; − 0.43)

2.21*** (1.11; 3.31)

6.42** (2.68; 10.16)

 (high)

72

− 8.9** (− 14.36; − 3.45)

− 5.47** (− 8.86; − 2.09)

1.90 (− 2.51; 6.31)

− 22.5(− 62.3; 17.29)

− 10.62** (− 16.81; − 4.44)

− 4.54** (− 7.9; − 1.18)

4.29*** (2.89; 5.70)

15.31*** (10.52; 20.11)

HbA1c (low)

159

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 (middle)

169

− 1.23 (− 4.53; 2.08)

− 1.26 (− 3.30; 0.79)

0.35 (− 2.40; 3.09)

− 0.21 (− 24.52; 24.11)

− 0.25 (− 3.91; 3.41)

− 0.49 (− 2.49; 1.51)

− 0.45 (− 1.28; 0.39)

− 0.99 (− 3.75; 1.76)

 (high)

21

6.24 (− 4.98; 17.47)

1.31 (− 5.65; 8.26)

7.92 (− 1.41; 17.25)

58.2 (− 24.41; 140.82)

7.05 (− 5.68; 19.78)

2.22 (− 4.73; 9.17)

− 3.28* (− 6.13; − 0.42)

− 8.44 (− 17.86; 0.97)

LDL-C (low)

103

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 (middle)

149

− 1.41 (− 5.06; 2.24)

− 1.19 (− 3.43; 1.05)

− 1.91 (− 4.91; 1.1)

− 1.60 (− 28.45; 25.26)

1.15 (− 2.88; 5.18)

0.19 (− 2.00; 2.38)

− 0.38 (− 1.32; 0.55)

− 0.19 (− 3.28; 2.89)

 (high)

97

− 6.75** (− 10.96; − 2.54)

− 5.16*** (− 7.74; − 2.58)

− 2.77 (− 6.23; 0.69)

− 33.48* (− 64.41; − 2.55)

− 6.14* (− 10.82; − 1.46)

− 3.54* (− 6.09; − 1.00)

0.05 (− 1.01; 1.12)

1.22 (− 2.29; 4.73)