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Table 4 Comparison of demographic and CMR data for subjects with and without ventricular arrhythmias during follow-up

From: Left ventricular fibro-fatty replacement in arrhythmogenic right ventricular dysplasia/cardiomyopathy: prevalence, patterns, and association with arrhythmias

 

Ventricular arrhythmia (n = 37)

No ventricular arrhythmia (n = 36)

p-value

Demographics and clinical

 Age (years)

34.3 ± 13.6

34.2 ± 13.6

0.85

 Male sex (%)

25 (67.6)

12 (33.3)

0.005

 Gene positive (%)

17 (46.0)

18 (50.0)

0.82

 VT prior to CMR (%)

25 (67.6)

4 (11.1)

 < 0.001

RV CMR findings

 RV WMA (%)

34 (91.9)

20 (55.6)

 < 0.001

 RV Fat (%)

14 (37.8)

8 (22.2)

0.20

 RV LGE (%)

11 (29.7)

2 (5.6)

0.012

 RVEDVI (mL/m2)

119.7 ± 30.2

93.4 ± 25.9

 < 0.001

 RVEF (%)

37.5 ± 7.8

46.0 ± 10.3

 < 0.001

LV CMR findings

 LV WMA (%)

5 (13.5)

4 (11.1)

1.000

 LV fat (%)

17 (45.9)

8 (22.2)

0.048

 LV fat in a bite pattern (%)

12 (32.4)

2 (5.6)

0.006

 LV LGE (%)

18 (48.7)

9 (25.0)

0.052

 LV fat and/or LGE (%)

20 (54.1)

11 (30.6)

0.059

 LVEDVI (mL/m2)

93.8 ± 21.7

84.7 ± 16.6

0.011

LVEF (%)

53.8 ± 6.8

54.4 ± 6.5

0.45

Low LVEF (< 50%) (%)

10 (27.0)

8 (22.2)

0.79

Any LV Involvement

22 (59.5)

15 (41.7)

0.16

CMR task force criteria

 Any TFC for CMR (%)

34 (92.2)

13 (35.9)

 < 0.001

 TFC for CMR major (%)

30 (81.1)

10 (27.8)

 < 0.001

 TFC for CMR minor (%)

4 (11.1)

3 (8.1)

1.000

 Total TFC Score

7 (IQR 6–8)

5 (IQR 5–6)

 < 0.001

  1. RV right ventricle, VT ventricular tachycardia, LV left ventricle, WMA wall motion abnormality, LGE late gadolinium enhancement, RVEDVI right ventricular end-diastolic volume indexed to body surface area, RVEF right ventricular ejection fraction, LVEDVI LV end-diastolic volume indexed to body surface area, LVEF LV ejection fraction, TFC task force criteria