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Table 4 Sensitivity, Specificity, PPV, NPV, Accuracy and Cohen’s kappa of 3D CMR VWI images analysis using DSA as reference

From: Assessment of carotid atherosclerotic disease using three-dimensional cardiovascular magnetic resonance vessel wall imaging: comparison with digital subtraction angiography

VariablesSensitivitySpecificityPPVNPVAccuracyCohen’s kappa
CMR1CMR2CMR1CMR2CMR1CMR2CMR1CMR2CMR1CMR2CMR1CMR2
Total Occlusion (n = 29)100.0 (100.0,100.0)100.0 (100.0,100.0)98.0 (95.3,100.0)98.0 (95.3,100.0)93.5 (84.9,100.0)93.5 (84.9,100.0)100.0 (100.0,100.0)100.0 (100.0,100.0)98.5 (96.3,100.0)98.5 (96.3,100.0)0.96 (0.79,1.00)0.96 (0.79,1.00)
Ulcer (n = 20)80.0 (62.5,97.5)85.0 (69.4,100.0)99.1 (97.3,100.0)98.2 (95.7,100.0)94.1 (82.9,100)89.5 (75.7,100.0)96.4 (93.1,99.9)97.3 (94.3,100.0)96.2 (92.8,99.5)96.2 (92.8,99.5)0.84 (0.67,1.00)0.85 (0.68,1.00)
Stenosis (%)
 >50% (n = 60)98.4 (95.2,100.0)96.8 (92.4,100.0)100.0 (100.0,100.0)98.5 (95.7,100.0)100.0 (100.0,100.0)98.4 (95.2,100.0)98.6 (95.8,100.0)97.1 (93.1,100.0)99.2 (97.7,100.0)97.7 (95.1,100.0)0.99 (0.81,1.00)0.95 (0.78,1.00)
 >70% (n = 38)97.4 (92.5,100.0)97.4 (92.5,100.0)94.5 (89.8,99.2)97.8 (94.8,100.0)88.4 (78.8,98.0)95.0 (88.2,100.0)98.9 (96.6,100.0)98.9 (96.7,100.0)95.4 (91.8,99.0)97.7 (95.1,100.0)0.89 (0.72,1.00)0.95 (0.77,1.00)
  1. All data, except for Cohen’s kappa, are percentages. Numbers in parentheses are 95% CI
  2. 3D CMR VWI, cardiovascular magnetic resonance three-dimensional vessel wall imaging; DSA, digital subtraction angiography; NPV, negative predictive value; PPV, positive predictive value