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Table 4 Sensitivity, Specificity, PPV, NPV, Accuracy and Cohen’s kappa of 3D CMR VWI images analysis using DSA as reference

From: Assessment of carotid atherosclerotic disease using three-dimensional cardiovascular magnetic resonance vessel wall imaging: comparison with digital subtraction angiography

Variables

Sensitivity

Specificity

PPV

NPV

Accuracy

Cohen’s kappa

CMR1

CMR2

CMR1

CMR2

CMR1

CMR2

CMR1

CMR2

CMR1

CMR2

CMR1

CMR2

Total Occlusion (n = 29)

100.0 (100.0,100.0)

100.0 (100.0,100.0)

98.0 (95.3,100.0)

98.0 (95.3,100.0)

93.5 (84.9,100.0)

93.5 (84.9,100.0)

100.0 (100.0,100.0)

100.0 (100.0,100.0)

98.5 (96.3,100.0)

98.5 (96.3,100.0)

0.96 (0.79,1.00)

0.96 (0.79,1.00)

Ulcer (n = 20)

80.0 (62.5,97.5)

85.0 (69.4,100.0)

99.1 (97.3,100.0)

98.2 (95.7,100.0)

94.1 (82.9,100)

89.5 (75.7,100.0)

96.4 (93.1,99.9)

97.3 (94.3,100.0)

96.2 (92.8,99.5)

96.2 (92.8,99.5)

0.84 (0.67,1.00)

0.85 (0.68,1.00)

Stenosis (%)

 >50% (n = 60)

98.4 (95.2,100.0)

96.8 (92.4,100.0)

100.0 (100.0,100.0)

98.5 (95.7,100.0)

100.0 (100.0,100.0)

98.4 (95.2,100.0)

98.6 (95.8,100.0)

97.1 (93.1,100.0)

99.2 (97.7,100.0)

97.7 (95.1,100.0)

0.99 (0.81,1.00)

0.95 (0.78,1.00)

 >70% (n = 38)

97.4 (92.5,100.0)

97.4 (92.5,100.0)

94.5 (89.8,99.2)

97.8 (94.8,100.0)

88.4 (78.8,98.0)

95.0 (88.2,100.0)

98.9 (96.6,100.0)

98.9 (96.7,100.0)

95.4 (91.8,99.0)

97.7 (95.1,100.0)

0.89 (0.72,1.00)

0.95 (0.77,1.00)

  1. All data, except for Cohen’s kappa, are percentages. Numbers in parentheses are 95% CI
  2. 3D CMR VWI, cardiovascular magnetic resonance three-dimensional vessel wall imaging; DSA, digital subtraction angiography; NPV, negative predictive value; PPV, positive predictive value