The association of secondary hyperparathyroidism and myocardial damages in hemodialysis end-stage renal disease patients: assessed by cardiovascular magnetic resonance native T1 mapping

Table 3 LV function, myocardial strain and native T1 value of ESRD with targeted iPTH and with increased iPTH

	Normal subjects (n = 30)	ESRD with targeted iPTH (n = 32)	ESRD with increased iPTH (n = 40)
LV function
EF (%)	65.0 ± 4.5	55.9 ± 12.0*	51.7 ± 12.8*
EDV (mL)	117 ± 31	128 ± 44	134 ± 50
ESV (mL)	45 ± 13	60 ± 44	69 ± 47*
SV (mL)	79 ± 17	67 ± 18	65 ± 18
LV mass (g)	52 ± 17	85 ± 31*	90 ± 32*
EDV/BSA (mL/mm²)	72.3 ± 20.1	83.3 ± 26.4	84.8 ± 36.3
ESV/BSA (mL/m²)	260.0 ± 5.5	38.9 ± 26.4	43.8 ± 34.4 *
SV/BSA (mL/m²)	48.6 ± 11.2	44.2 ± 11.6	40.3 ± 10.9*
Mass/BSA (g/m²)	32.2 ± 11.4	54.4 ± 19.0*	56.3 ± 19.0*
Myocardial strain parameters
PRS	43.0 ± 9.8	43.2 ± 14.9	37.6 ± 15.7
PCS	− 18.3 ± 2.1	− 17.8 ± 4.2	− 16.8 ± 5.0
PLS	− 16.5 ± 2.4	− 15.7 ± 3.7	− 14.8 ± 4.4
Native T1 value
Basal segment	1238 ± 36	1304 ± 41*	1330 ± 43*#
Middle segment	1242 ± 50	1300 ± 43*	1323 ± 43*#
Apical segment	1280 ± 65	1339 ± 86	1360 ± 74*
Global	1251 ± 49	1305 ± 41*	1334 ± 40*#

LV left ventricular, EDV end-diastolic volume, ESV end-systolic volume, EF ejection fraction, SV stroke volume, PRS peak radial strain, PCS peak circumferential strain, PLS peak longitudinal strain directions, BSA body surface area. Other abbreviations are the same as Tables 1 and 2
*P < 0.05 vs. normal group; ^#P < 0.05 vs. comparison with ESRD with targeted iPTH

ISSN: 1532-429X