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Table 4 Difference in response to adenosine doses divided by HR response to standard dose

From: A comparison of standard and high dose adenosine protocols in routine vasodilator stress cardiovascular magnetic resonance: dosage affects hyperaemic myocardial blood flow in patients with severe left ventricular systolic impairment

 

Standard dose

High dose

p

Non-responders (n = 24)

Rest HR (bpm)

67 ± 16

68 ± 14

0.789

Stress HR (bpm)

70 ± 14

75 ± 12

0.034

Increase in HR (bpm)

3 ± 6

7 ± 11

0.053

Stress MBF (ml/g/min)

1.35 ± 0.49

1.45 ± 0.46

0.188

MPR

1.93 ± 0.77

2.05 ± 0.70

0.215

Adequate HR response (n = 36)

Rest HR (bpm)

69 ± 12

70 ± 13

0.461

Stress HR (bpm)

88 ± 15

89 ± 18

0.762

Increase in HR (bpm)

19 ± 9

19 ± 13

0.838

Stress MBF (ml/g/min)

1.48 ± 0.60

1.59 ± 0.43

0.103

MPR

2.32 ± 0.86

2.53 ± 0.63

0.073

  1. Stress HR was significantly higher with high dose adenosine in the non-responder group only. Non-responders and responders were defined by heart rate increase with adenosine of < 10 bpm or ≥ 10 bpm. There data are from patients only. No difference was seen in stress MBF in either group
  2. Data given as mean ± standard deviation or n (%)
  3. HR heart rate, MBF myocardial blood flow
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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