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Fig. 8 | Journal of Cardiovascular Magnetic Resonance

Fig. 8

From: In vivo calibration of the T2* cardiovascular magnetic resonance method at 1.5 T for estimation of cardiac iron in a minipig model of transfusional iron overload

Fig. 8

Segmental and transmural distribution of myocardial iron. One mid-myocardial slice was cut from formalin-fixed dextran iron-loaded hearts. Formalin-fixed hearts were available from 11 pigs (7, 8, 12, 13, 14, 16, 17, 18, 19, 20, and 21). The slice was cut into 6 segments: Anteroseptal (1), inferolateral (2), inferior (3), inferoseptal (4), anterolateral (5) and anterior (6). Each section was divided into an epicardial-, mesocardial and endocardial layer, leading to 18 samples from each heart for assessment of chemical CIC (for details see Fig. 2 and the Results). a to f display segmental and transmural CIC values for each  pig. g to l display the corresponding mean CIC levels of all 11  pigs for each of the 18 different samples given in mg Fe/g. Significant differences are indicated by horizontal bars and p-values. Label panel gives weekly dextran-iron dose for each  pig in mg Fe/kg BW

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