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Table 1 Patient characteristics

From: Rapid ascending aorta stiffening in bicuspid aortic valve on serial cardiovascular magnetic resonance evaluation: comparison with connective tissue disorders

Parameter

BAV (n = 49)

CTD (n = 50)

p value

Age at first CMR (years)

23.0 ± 11

20.6 ± 12

0.30

Male gender

36 (73%)

32 (64%)

0.26

Type of BAV

 

N/A

N/A

Left–right

22 (45%)

  

Right-non

11 (22%)

  

Left-non

1 (2%)

  

Unicuspid

15 (31%)

  

Type of CTD

N/A

 

N/A

Marfan syndrome

 

26 (52%)

 

Nonspecific CTD

 

14 (28%)

 

Loeys-Dietz syndrome

 

7 (14%)

 

Ehlers-Danlos syndrome

 

3 (6%)

 

Aortic regurgitation

 < 0.001

 None/trivial

12 (25%)

47 (94%)

 

 Mild

30 (63%)

3 (6%)

 

 Moderate

5 (10%)

0

 

 Severe

1 (2%)

0

 

 Not available

1 (2%)

0 (0%)

 

Aortic stenosis

 < 0.001

 Mild or less

23 (50%)

50 (100%)

 

 Moderate

22 (48%)

0

 

 Severe

1 (2%)

0

 

 Not available

2 (4%)

0

 

 β blocker and/or ARB use

30 (61%)

24 (48%)

0.22

  1. ARB denotes angiotensin receptor blocker, BAV bicuspid aortic valve, CTD connective tissue disorders. The severity of aortic regurgitation and stenosis was assessed by echocardiography