|
Parameter
|
BAV (n = 49)
|
CTD (n = 50)
|
p value
|
|---|
|
Age at first CMR (years)
|
23.0 ± 11
|
20.6 ± 12
|
0.30
|
|
Male gender
|
36 (73%)
|
32 (64%)
|
0.26
|
|
Type of BAV
| |
N/A
|
N/A
|
|
Left–right
|
22 (45%)
| | |
|
Right-non
|
11 (22%)
| | |
|
Left-non
|
1 (2%)
| | |
|
Unicuspid
|
15 (31%)
| | |
|
Type of CTD
|
N/A
| |
N/A
|
|
Marfan syndrome
| |
26 (52%)
| |
|
Nonspecific CTD
| |
14 (28%)
| |
|
Loeys-Dietz syndrome
| |
7 (14%)
| |
|
Ehlers-Danlos syndrome
| |
3 (6%)
| |
|
Aortic regurgitation
|
< 0.001
|
|
None/trivial
|
12 (25%)
|
47 (94%)
| |
|
Mild
|
30 (63%)
|
3 (6%)
| |
|
Moderate
|
5 (10%)
|
0
| |
|
Severe
|
1 (2%)
|
0
| |
|
Not available
|
1 (2%)
|
0 (0%)
| |
|
Aortic stenosis
|
< 0.001
|
|
Mild or less
|
23 (50%)
|
50 (100%)
| |
|
Moderate
|
22 (48%)
|
0
| |
|
Severe
|
1 (2%)
|
0
| |
|
Not available
|
2 (4%)
|
0
| |
|
β blocker and/or ARB use
|
30 (61%)
|
24 (48%)
|
0.22
|
- ARB denotes angiotensin receptor blocker, BAV bicuspid aortic valve, CTD connective tissue disorders. The severity of aortic regurgitation and stenosis was assessed by echocardiography
