Presence of sarcomere gene mutation group (n = 41) | Absence of sarcomere gene mutation group (n = 92) | P | |
---|---|---|---|
LVEDV, mL | 133.6 ± 28.6 | 135.7 ± 28.2 | 0.698 |
LVESV, mL | 51.7 ± 23.1 | 46.9 ± 18.5 | 0.208 |
LV mass, g | 153.7 ± 37.2 | 152.8 ± 48.0 | 0.913 |
LV mass index, g/m2 | 88.0 ± 21.1 | 84.7 ± 23.8 | 0.456 |
LV mass/volume ratio | 1.19 ± 0.32 | 1.14 ± 0.32 | 0.469 |
LV ejection fraction, % | 62.5 ± 9.4 | 65.7 ± 9.8 | 0.077 |
Segmental* thickness, mm | |||
Thickness in anteroseptal segments | 13.0 ± 2.9 | 11.7 ± 3.2 | 0.025 |
Thickness in septal segments | 14.4 ± 3.4 | 12.5 ± 3.6 | 0.005 |
Thickness in inferoposterior segments | 8.6 ± 2.1 | 8.9 ± 1.8 | 0.484 |
Thickness in lateral segments | 7.6 ± 2.2 | 8.6 ± 2.1 | 0.020 |
Thickness in apical segments | 10.5 ± 3.2 | 10.7 ± 3.9 | 0.771 |
Late gadolinium enhancement (LGE) | |||
Presence of LGE in LV, n (%) | 37(90) | 55(60) | < 0.001 |
Number of LGE segments in LV | 4.9 ± 2.8 | 2.9 ± 3.5 | 0.002 |
% LGE amount of LV | 10.6 ± 10.1 | 6.4 ± 9.3 | 0.040 |
LGE in anteroseptal segments, % | 46.3 ± 25.7 | 20.7 ± 26.2 | < 0.001 |
LGE in septal segments, % | 47.8 ± 30.0 | 18.0 ± 26.2 | < 0.001 |
LGE in inferoposterior segments, % | 7.8 ± 14.8 | 13.5 ± 24.5 | 0.609 |
LGE in lateral segments, % | 16.6 ± 20.4 | 14.4 ± 24.3 | 0.171 |
LGE in apical segments, % | 36.0 ± 37.9 | 29.1 ± 37.5 | 0.331 |
T2, ms | |||
T2 average of 16 segments | 56.1 ± 3.5 | 55.3 ± 3.0 | 0.177 |
T2 in anteroseptal segments | 56.9 ± 3.7 | 55.3 ± 3.0 | 0.242 |
T2 in septal segments | 57.9 ± 4.0 | 57.2 ± 3.7 | 0.360 |
T2 in inferoposterior segments | 55.9 ± 3.7 | 54.8 ± 3.3 | 0.117 |
T2 in lateral segments | 54.9 ± 4.0 | 54.0 ± 3.3 | 0.193 |
T2 in apical segments | 57.1 ± 5.6 | 56.7 ± 4.3 | 0.677 |
Native T1, ms | |||
T1 average of 16 segments | 1025 ± 47 | 1019 ± 49 | 0.512 |
T1 in anteroseptal segments | 1023 ± 46 | 1017 ± 51 | 0.524 |
T1 in septal segments | 10343 ± 44 | 1024 ± 49 | 0.301 |
T1 in inferoposterior segments | 1045 ± 59 | 1032 ± 54 | 0.216 |
T1 in lateral segments | 1014 ± 59 | 1013 ± 54 | 0.921 |
T1 in apical segments | 1009 ± 66 | 1017 ± 58 | 0.469 |
Post contrast T1, ms | |||
T1 average of 16 segments | 579 ± 59 | 607 ± 63 | 0.021 |
T1 in anteroseptal segments | 569 ± 66 | 603 ± 64 | 0.008 |
T1 in septal segments | 574 ± 66 | 608 ± 63 | 0.007 |
T1 in inferoposterior segments | 595 ± 53 | 616 ± 63 | 0.065 |
T1 in lateral segments | 590 ± 56 | 611 ± 65 | 0.085 |
T1 in apical segments | 564 ± 57 | 588 ± 66 | 0.051 |
Extracellular volume fraction (ECV), % | |||
ECV average of 16 segments | 34.2 ± 4.8 | 31.4 ± 4.3 | 0.001 |
ECV in anteroseptal segments | 35.8 ± 6.8 | 31.8 ± 4.4 | 0.001 |
ECV in septal segments | 35.7 ± 6.7 | 31.4 ± 4.1 | < 0.001 |
ECV in inferoposterior segments | 32.7 ± 4.0 | 30.8 ± 4.5 | 0.022 |
ECV in lateral segments | 31.8 ± 3.9 | 30.7 ± 5.1 | 0.235 |
ECV in apical segments | 35.3 ± 4.6 | 33.7 ± 5.5 | 0.118 |