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Table 1 Baseline and CMR Characteristics of Patients with and without Myocardial Ischemia (N = 1342)

From: Prognostic value of stress cardiovascular magnetic resonance in asymptomatic patients with known coronary artery disease

  All patients
(N = 1342)
No ischemia
(N = 966)
Ischemia
(N = 376)
p value
Age (years) 67.7 ± 10.5 67.2 ± 10.7 69.0 ± 9.3 0.003
Males, n (%) 1101 (82.0) 781 (80.8) 320 (85.1) 0.024
Body mass index (kg/m2) 27.2 ± 4.0 27.1 ± 3.9 27.5 ± 4.0 0.135
Coronary risk factors, n (%)     
 Diabetes mellitus 409 (30.5) 258 (26.7) 151 (40.2)  < 0.001
 Hypertension 691 (51.5) 468 (48.4) 223 (59.3)  < 0.001
 Dyslipidemia 849 (63.3) 589 (61.0) 260 (69.1) 0.006
 Current or previous smoking 324 (24.1) 244 (25.3) 80 (21.3) 0.144
 Family history of CAD 431 (32.1) 309 (32.0) 122 (32.4) 0.923
 Obesitya 310 (23.1) 220 (22.8) 90 (23.9) 0.703
Medical history of CV disease, n (%)     
 Prior PCI 735 (54.8) 552 (57.1) 183 (48.7) 0.006
 Prior CABG 431 (32.1) 309 (32.0) 122 (32.4) 0.923
 Prior MI 746 (55.6) 570 (59.0) 176 (46.8)  < 0.001
 Peripheral atheroma 115 (8.6) 64 (6.6) 51 (13.6)  < 0.001
 Ischemic stroke 35 (2.6) 28 (2.9) 7 (1.9) 0.379
 Pacemaker 2 (0.1) 1 (0.1) 1 (0.3) 0.482
 Renal failureb 16 (1.2) 12 (1.2) 4 (1.1) 1.000
 Heart failure hospitalization 31 (2.3) 24 (2.5) 7 (1.9) 0.631
Indications to stress CMR (multiple possible), n (%)     
 PCI or CABG follow-upc 1184 (88.2) 830 (85.9) 354 (94.1)  < 0.001
 Inconclusive stress test 107 (8.0) 65 (6.7) 42 (11.2) 0.01
 Inconclusive CCTAd 110 (8.2) 60 (6.2) 50 (13.3)  < 0.001
Cardiac rhythm, n (%)     
 Sinus rhythm 1151 (85.8) 818 (84.7) 333 (88.6)  
 Sinus rhythm with extrasystoles 185 (13.8) 145 (15.0) 40 (10.6) 0.039
 Atrial fibrillation/supraventricular arrhythmias 6 (0.4) 3 (0.3) 3 (0.8)  
LV ejection fraction, % 45.8 ± 12.5 45.1 ± 12.5 47.7 ± 12.5 < 0.001
LV end-diastolic volume index, ml/m2 100.2 ± 31.3 102.2 ± 32.1 95.1 ± 28.4  < 0.001
LV end-systolic volume index, ml/m2 57.1 ± 27.4 58.9 ± 27.7 52.2 ± 25.8  < 0.001
LV mass, g/m2 73.8 ± 7.1 73.6 ± 7.2 73.5 ± 7.1 0.319
RV ejection fraction, % 57.2 ± 11.2 57.1 ± 11.3 57.3 ± 12.9 0.429
Presence of LGE, n (%) 689 (51.3) 502 (52.0) 187 (49.7) 0.018
Presence of viabilitye, n (%) 280 (20.9) 175 (18.1) 105 (27.9)  < 0.001
 Number of segments of LGE 2.3 ± 1.9 2.4 ± 1.9 2.2 ± 2.0 0.268
 Number of segments of myocardial ischemia 0.7 ± 1.5 0.0 ± 0.0 2.5 ± 1.7  < 0.001
HR at baseline, beats/min 67 ± 12 67 ± 12 71 ± 13 0.512
HR at stress, beats/min 91 ± 9 90 ± 9 96 ± 11 0.069
RPP at baseline (k), mmHg-beats/min 9.1 (7.5–10.6) 9.0 (7.5–10.6) 9.2 (7.5–11.0) 0.621
RPP at stress (k), mmHg-beats/min 10.6 (9.0–12.4) 10.4 (9.0–12.4) 10.9 (9.5–12.8) 0.193
  1. Values are n (%), mean ± SD, or median (interquartile range)
  2. BMI body mass index, CABG coronary artery bypass grafting, CAD coronary artery disease, CCTA coronary computed tomography angiography, CMR cardiovascular magnetic resonance, CV cardiovascular disease, GFR glomerular filtration rate, HF heart failure, HR heart rate, LGE late gadolinium enhancement, LV left ventricle, MI myocardial infarction, PCI percutaneous coronary intervention, RPP rate-pressure product (pressure mmHg x Heart rate bpm)/1000, RV right ventricle, SD standard deviation
  3. aBMI ≥ 30 kg/m2
  4. bGlomerular filtration rate < 60 ml/min/1.73 m2
  5. cTo detect myocardial ischemia in asymptomatic patient every 3 to 5 years in accordance with ESC guidelines. (REF)
  6. dCoronary stenosis of unknown significance on CCTA
  7. ePresence of LGE with < 50% transmurality