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Table 2 CMR measures of left ventricular and right ventricular anatomy, function, native T1 and T2 in patients with idiopathic LBBB

From: Presence of contractile impairment appears crucial for structural remodeling in idiopathic left bundle-branch block

CMR measurements

Idiopathic LBBB (n = 53)

Control group A CVRF ( +) (n = 53)

Control group B CVRF (−) (n = 26)

p (LBBB vs. control group A)

p (LBBB vs. control group B)

LVEF (%)

53.7 ± 4.6

62.9 ± 4.2

64.4 ± 5.0

 < 0.001

 < 0.001

sMAPSE (mm)

11 (10–12.5)

13 (11–14)

13 (11–16)

 < 0.01

 < 0.001

GCS

− 17.5 ± 3.0

− 20.5 ± 2.5

− 21.5 ± 2.2

 < 0.001

 < 0.0001

GLS

− 15.7 ± 3.0

− 18.2 ± 2.3

− 19.7 ± 3.2

 < 0.001

 < 0.0001

LVEDV (ml)

156.6 ± 39.3

135.5 ± 24.8

133.3 ± 28.0

 < 0.01

 < 0.01

LVEDVI (ml/m2)

82.5 ± 14.9

71.8 ± 9.9

71.4 ± 13.1

 < 0.001

 < 0.01

RVEDV (ml)

129.9 ± 30.5

130.3 ± 31.4

141.3 ± 33.9

0.940

0.228

RVEDVI (ml/m2)

68.4 ± 11.3

68.8 ± 11.8

73.3 ± 13.9

0.871

0.181

RVEF (%)

64.4 ± 6.6

65.0 ± 6.7

61.8 ± 6.3

0.641

0.191

TAPSE (mm)

21 (19–24)

22 (19.5–26)

22 (19–25)

0.120

0.346

LV mass (g)

97 ± 27

88 ± 22

87 ± 20

0.077

0.104

Native T1

1.5 T

n = 22

n = 21

n = 13

  

 Global (ms)

1023 ± 25

1009 ± 20

1000 ± 20

0.060

 < 0.05

 Septal (ms)

1046 ± 30

1022 ± 22

1006 ± 17

 < 0.01

 < 0.001

 Lateral (ms)

1017 ± 27

1006 ± 29

988 ± 28

0.185

 < 0.01

3 T

n = 19

n = 26

n = 13

  

 Global (ms)

1260 ± 39

1238 ± 25

1216 ± 64

 < 0.05

 < 0.05

 Septal (ms)

1293 ± 56

1256 ± 30

1252 ± 26

 < 0.01

0.062

 Lateral (ms)

1225 ± 42

1226 ± 30

1219 ± 37

0.981

0.723

T2

1.5 T

n = 12

n = 19

n = 12

  

 Global (ms)

53.5 ± 2.3

53.8 ± 1.8

52.1 ± 1.8

0.094

0.709

3 T

n = 6

n = 24

n = 11

  

 Global (ms)

45.9 ± 3.0

47.7 ± 2.3

46.5 ± 2.6

0.137

0.698

  1. CVRF cardiovascular risk factors, LBBB left bundle-branch block, LV left ventricle, EDV end-diastolic volume, EDVI end-diastolic volume index, EF ejection fraction, sMAPSE septal mitral annular plane systolic excursion, GCS global circumferential strain, GLS global longitudinal strain, RV right ventricle, TAPSE tricuspid annular plane systolic excursion; Comparison of native T1 and T2 between LBBB patients and controls in 1.5 T and 3 T: Values are mean ± SD or median (interquartile range)