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Table 5 Comparison of idiopathic LBBB patients with isolated ventricular asynchrony, with superimposed contractile impairment and control group B without cardiovascular risk factors

From: Presence of contractile impairment appears crucial for structural remodeling in idiopathic left bundle-branch block

CMR measurements

LBBB with isolated asynchrony (n = 33)

LBBB with superimposed hypocontractility (n = 20)

Control group B CVRF (−) (n = 26)

ANOVA

p

Bonferroni Post-Hoc

LBBB with isolated asynchrony vs. control group B

LBBB with superimposed hypocontractility vs. control group B

LBBB with isolated asynchrony vs. LBBB with superimposed hypocontractility

LVEDVI (ml/m2)

78.1 ± 14.3

89.8 ± 14.0

71.4 ± 13.1

 < 0.001

 < 0.01

0.013

 < 0.0001

corrected LV-EF (%)

62.9 ± 3.6

55.9 ± 2.8

64.4 ± 5.0

 < 0.001

 < 0.001

0.450

 < 0.001

RVEDVI (ml/m2)

65.0 ± 9.7

74.2 ± 11.7

73.3 ± 13.9

 < 0.05

 < 0.05

0.072

1.000

RV-EF (%)

66.9 ± 5.3

60.4 ± 6.8

61.8 ± 6.3

 < 0.05

 < 0.01

0.294

1.000

GCS

− 18.5 ± 2.9

− 15.9 ± 2.4

− 21.5 ± 2.2

 < 0.001

 < 0.01

 < 0.001

 < 0.001

GLS

− 16.4 ± 3.3

− 14.5 ± 1.8

− 19.7 ± 3.2

 < 0.001

 < 0.05

 < 0.001

 < 0.001

LV mass (g)

93 ± 25

103 ± 30

87 ± 20

0.090

0.420

1.000

0.088

Native T1 times

1.5-T

n = 14

n = 8

n = 13

    

 Global (ms)

1015 ± 24

1035 ± 24

1000 ± 20

 < 0.01

0.144

0.303

 < 0.05

 Septal (ms)

1039 ± 24

1059 ± 36

1006 ± 17

 < 0.001

0.271

 < 0.05

 < 0.001

 Lateral (ms)

1015 ± 30

1021 ± 23

988 ± 28

 < 0.05

1.000

0.069

0.050

3-T

n = 11

n = 8

n = 13

    

 Global (ms)

1253 ± 35

1271 ± 43

1216 ± 64

0.056

0.651

0.275

0.070

 Septal (ms)

1282 ± 54

1308 ± 60

1252 ± 26

0.096

0.578

0.614

0.097

 Lateral (ms)

1222 ± 28

1230 ± 57

1219 ± 37

0.850

1.000

1.000

1.000

  1. LBBB left bundle-branch block, CVRF cardiovascular risk factors, LV left ventricle, EDV end-diastolic volume, EDVI end-diastolic volume undex, EF ejection fraction, RV right ventricle; GCS global circumferential strain, GLS global longitudinal strain. Values are mean ± standard deviation. Differences between all three groups were calculated using 2-way ANOVA and Bonferroni-Posttest