Prognostic value of fast semi-automated left atrial long-axis strain analysis in hypertrophic cardiomyopathy

Table 2 Cardiovascular magnetic resonance (CMR) left ventricular (LV) and right ventricular (RV) parameters of HCM patients and healthy subjects

Variable	Healthy subjects (n = 100)	HCM (n = 359)	P	HCM Patients without combined outcome (n = 300)	HCM Patients with combined outcome (n = 59)	P	HCM Patients with LA diameter > 41 mm (n = 135)	HCM Patients with LA diameter ≤ 41 mm (n = 224)	P
LVEF (%)	66.7 (62.3,70.4)	64.3 (58.7,68.9)	0.001*	64.6 (59.2,69.2)	62.3 (58.2,67.6)	0.044*	63.3 (56.8,69.2)	64.8 (59.4,68.7)	0.130
LVEDVI (mL/ m²)	71.7 (63.0,80.8)	78.5 (68.3,91.2)	< 0.001*	77.5 (68.3,87.8)	86.2 (29.2,108.8)	0.004*	85.2 (73.1,99.9)	76.3 (66.5,84.7)	< 0.001*
LVESVI (mL/ m²)	23.9 (19.4,29.2)	28.3 (21.9,34.9)	< 0.001*	27.5 (21.7,34.3)	32.9 (25.0,39.1)	0.002*	30.6 (23.2,38.8)	27.1 (21.3,33.9)	0.001*
RVEF (%)	60.8 (58.1,64.3)	62.0 (55.7,67.4)	0.291	61.4 ± 8.8	60.1 ± 9.2	0.260	61.2 (55.4,67.3)	62.1 (56.0,67.5)	0.274
RVEDVI (mL/ m²)	66.6 (57.5,78.2)	65.8 (55.0,74.0)	0.162	67.0 ± 15.3	61.8 ± 14.6	0.059	64.7 (56.0,72.3)	66.5 (55.0,75.8)	0.246
RVESVI (mL/ m²)	26.4 (22.4,30.9)	24.2 (19.1,30.9)	0.024*	24.4 (19.1,31.0)	24.0 (18.9,29.1)	0.538	24.2 (19.7,30.1)	24.1 (18.0,31.0)	0.775
LVMI (g/m²)	49.6 (43.5,54.0)	94.4 (74.9,115.4)	< 0.001*	92.2 (72.0,109.6)	99.5 (83.0,125.2)	0.006*	101.7 (82.3,124.5)	87.0 (69.3,107.3)	< 0.001*
Max WT (mm)	–	21.8 (18.1,26.0)	–	21.5 (18.0,25.8)	22.9 (20.1,26.5)	0.143	22.4 (19.1,26.0)	21.5 (17.5,26.0)	0.128
LGE extent (%)	–	5.7 (2.0,11.4)	–	5.4 (2.1,10.7)	8.3 (3.3,16.2)	0.014*	5.1 (1.6,11.8)	5.8 (2.1,11.3)	0.858

*p < 0.05; Data are expressed as mean ± SD, mean with 25th–75th percentiles in parentheses, or as a percentage for categorical variables. CMR = cardiovascular magnetic resonance; HCM hypertrophic cardiomyopathy, EDVI end-diastolic volume index, ESVI end-systolic volume index, LVEF left ventricular ejection fraction, RVEF right ventricular ejection fraction, LVMI LV mass index, Max WT maximal (LV) wall thickness, LGE late gadolinium enhancement, LV left ventricular, RV right ventricular

ISSN: 1532-429X