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Table 3 Threshold performance for models incorporating native T1, ɛls, and ɛcc

From: Non-contrast cardiovascular magnetic resonance detection of myocardial fibrosis in Duchenne muscular dystrophy

Outcome condition

Model fit equation

AUC

R2

Threshold

Sensitivity (%)

Specificity (%)

+ LR

− LR

Presence/absence LGE

0.0096 * (native T1) + 0.2263 * (ɛls) + 0.538 * (ɛcc)

0.74

0.21

0.473

81.1

42.3

1.4

0.45

    

0.839

74.3

69.2

2.4

0.37

    

1.512

44.6

96.2

11.7

0.58

 

LVEF (univariate)

0.81

–

56%

56.8

99.9

568

0.43

High (GSS 3–4) vs low (GSS 0–2) grade LGE

0.013 * (native T1) + 0.32 * (ɛls) + 0.059 * (ɛcc)

0.82

0.38

− 1.297

94.9

53.3

2.0

0.10

    

− 0.559

76.9

76.7

3.3

0.30

    

0.672

43.6

93.3

6.5

0.60

 

LVEF (univariate)

0.87

–

50%

63.8

93.8

10.3

0.39

  1. GSS global severity score, AUC area under the curve, + LR positive likelihood ration, − LR negative likelihood ratio, LVEF left ventricular ejection fraction