Long-term prognostic value of stress perfusion cardiovascular magnetic resonance in patients without known coronary artery disease

Table 3 Multivariable cox regression analysis for the prediction of adverse events

	MACE		Cardiovascular mortality
	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value
Model 1^a
Age	1.03 (1.01–1.05)	0.002	1.04 (1.02–1.07)	< 0.001
Male	1.91 (1.32–2.76)	< 0.001	1.85 (1.22–2.82)	0.004
Family history of coronary artery disease	0.74 (0.49–1.10)	0.131	0.66 (0.41–1.05)	0.076
LV end-systolic volume index, per 10 ml/m²	2.70 (0.99–7.37)	0.053	3.81 (1.38–10.5)	0.010
Model 2^b
Presence of unrecognized MI	1.82 (1.28–2.49)	< 0.001	1.76 (1.18–2.66)	0.007
Model 3^c
Presence of unrecognized MI	1.73 (1.22–2.45)	0.002	1.73 (1.15–2.62)	0.009
Presence of ischemia	3.71 (2.73–5.05)	< 0.001	3.13 (2.17–4.51)	< 0.001

CI confidence interval, MACE major adverse cardiac events, LV left ventricle, MI myocardial infarction
^aCovariates in the model 1 by stepwise variable selection with entry and exit criteria set at the p ≤ 0.2 level: for MACE: age, male, hypertension, family history of CAD, LVEF per 10%, LV end-systolic volume index, per 10 ml/m². for CV mortality: age, male, family history of CAD, family history of CAD
^bCovariates in the model 2: model 1 with unrecognized MI
^cCovariates in the model 3: model 1 with unrecognized MI and ischemia

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