Long-term prognostic value of stress perfusion cardiovascular magnetic resonance in patients without known coronary artery disease

Table 4 Discrimination and reclassification associated with ischemia and LGE for prediction of MACE

	MACE
	C-index (95%CI)	NRI (95%CI)	IDI (95%CI)
Model 1 (stepwise selection)^a	0.61 (0.56–0.65)	Reference	Reference
Model 2 (model 1 + unrecognized MI)^b	0.66 (0.60–0.71)	0.252 (0.065–0.439)	0.037 (0.016–0.058)
Model 3 (model 1 + unrecognized MI and ischemia)^c	0.72 (0.69–0.76)	0.431 (0.212–0.650)	0.053 (0.030–0.076)

CI confidence interval, IDI integrative discrimination index, MACE major adverse cardiac events, MI myocardial infarction, NRI net reclassification improvement
^aCovariates in the model 1 by stepwise variable selection with entry and exit criteria set at the p ≤ 0.2 level: age, male, hypertension, family history of coronary artery disease, LVEF per 10%, LV end-systolic volume index, per 10 ml/m²
^bCovariates in the model 2: model 1 with unrecognized MI
^cCovariates in the model 3: model 1 with unrecognized MI and ischemia

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