Table 2 Hemodynamics parameters derived from 4D Flow CMR
Characteristics | Overall (n = 12) | Stable (n = 4) | Enlarging (n = 8) | p-value |
|---|---|---|---|---|
Ascending aorta | ||||
Cardiac Output (l/min) | 4.9 ± 0.9 (range 3.3–6.4) | 5.1 ± 0.9 | 4.8 ± 1.0 | 0.621 |
Forward Flow (ml/beat) | 87.4 ± 21.7 (range 58.2–125.2) | 90.9 ± 24.7 | 85.7 ± 21.6 | 0.734 |
Reverse Flow (ml/beat) | − 7.7 ± 7.5 (range − 26.8−0.5) | − 5.2 ± 3.2 | − 8.9 ± 8.9 | 0.314 |
True lumen | ||||
Net flow (l/min) | 3.4 ± 1.1 (range 2.1–5.5) | 3.0 ± 1.0 | 3.6 ± 1.1 | 0.474 |
Peak velocity (cm/s) | 89 ± 32 (range 38–166) | 84 ± 7 | 91 ± 40 | 0.653 |
Maximum relative pressure (mmHg/m)* | 50 ± 11 (range 41–75) | 47 ± 8 | 52 ± 12 | 0.418 |
Minimum relative pressure (mmHg/m)* | − 22 ± 6 (range − 32 to − 15) | − 24 ± 6 | − 22 ± 6 | 0.654 |
False lumen | ||||
Net flow (l/min) | 1.5 ± 1.4 (range 0.1–4.6) | 1.9 ± 2.2 | 1.2 ± 0.9 | 0.596 |
Peak velocity at entry tear (cm/s) | 102 ± 10 (range 68–144) | 108 ± 12 | 99 ± 9 | 0.560 |
Peak velocity (cm/s) | 68 ± 31 (range 16–120) | 67 ± 40 | 69 ± 29 | 0.925 |
False lumen ejection fraction (%) | 36 ± 25 (range 0–88) | 10 ± 12 | 49 ± 18 | 0.002 |
Maximum systolic deceleration rate (cm/s3) | 1401 ± 956 (range 516–3201) | 1146 ± 782 | 1529 ± 1058 | 0.499 |
Maximum relative pressure (mmHg/m) | 41 ± 16 (range 21–72) | 57 ± 13 | 32 ± 11 | 0.017 |
Minimum relative pressure (mmHg/m) | − 21 ± 9 (range − 42 to − 11) | − 29 ± 10 | − 18 ± 7 | 0.105 |
Transseptal | ||||
Maximum relative pressure (mmHg/m)* | 35 ± 23 (range 1–66) | 25 ± 36 | 39 ± 18 | 0.585 |
Minimum relative pressure (mmHg/m)* | − 14 ± 11 (range − 34 to − 4) | − 14 ± 18 | − 14 ± 10 | 0.989 |