| TOF (n = 60) | Healthy control (n = 30) | P-value | TOF-PR (n = 38) | TOF-RVOTO (n = 22) | P-value* |
---|---|---|---|---|---|---|
Male, n (%) | 31 (51.7) | 15 (50.0) | 1.00 | 19 (50.0) | 12 (54.5) | 0.793 |
Age at repair (years) | 2.1 ± 3.6 |  |  | 1.1 ± 1.3 | 3.8 ± 5.4 | 0.031 |
Age at first CMR (years) | 23.6 ± 7.9 | 20.8 ± 3.1 | 0.061 | 24.2 ± 6.9 | 22.5 ± 9.4 | 0.404 |
Age at second CMR (years) | 25.2 ± 8.1 |  |  | 26.0 ± 7.0 | 23.7 ± 9.8 | 0.300 |
Age at PVR (years) | 23.8 ± 7.9 |  |  | 24.6 ± 6.9 | 22.6 ± 9.4 | 0.345 |
Time between first CMR and PVR, median (IQR) (years) | 0.25 (3 days, 0.38) |  |  | 0.30 (0.10, 0.56) | 0.01 (1d, 0.19) |  < 0.001 |
Time between PVR and second CMR, median (IQR) (years) | 1.00 (0.54, 1.74) | Â | Â | 1.06 (0.67, 7.19) | 0.57 (0.51, 1.69) | 0.078 |
Native anatomy | ||||||
 TOF-Pulmonary stenosis | 44 (73.3) |  |  |  |  |  |
 TOF-Pulmonary atresia | 16 (26.7) |  |  |  |  |  |
Additional anatomic features | ||||||
 Absent pulmonary valve | 3 (5.0) |  |  |  |  |  |
 Absent left pulmonary artery | 3 (5.0) |  |  |  |  |  |
 Discontinuous pulmonary arteries | 4 (6.7) |  |  |  |  |  |
 Atrioventricular canal defect | 1 (1.7) |  |  |  |  |  |
Initial repair, n (%) | ||||||
 Staged | 18 (30) |  |  |  |  |  |
 Complete | 42 (70) |  |  |  |  |  |
Type of complete repair, n (%) |  |  |  |  |  |  < 0.001 |
 Transannular patch | 34 (56.7) |  |  | 30 (78.9) | 4 (18.2) |  |
 RV-PA conduit | 15 (25.0) |  |  | 0 (0) | 15 (68.2) |  |
 Non-Transannular patch | 10 (16.7) |  |  | 7 (18.4) | 3 (13.6) |  |
 Unknown | 1 (1.7) |  |  | 1 (2.6) | 0 (0) |  |
Number of surgeries, n (%) |  |  |  |  |  |  < 0.001 |
 1 | 49 (81.7) |  |  | 37 (97.4) | 12 (54.5) |  |
 2 | 8 (13.3) |  |  | 1 (2.6) | 7 (31.8) |  |
  ≥ 3 | 3 (5.0) |  |  | 0 (0) | 3 (13.6) |  |
First PVR, n (%) |  |  |  |  |  |  < 0.001 |
 Yes | 51 (85.0) |  |  | 38 (100) | 13 (59.1) |  |
 No | 9 (15.0) |  |  | 0 (0) | 9 (40.9) |  |