Fig. 2From: Pulmonary arterial banding in mice may be a suitable model for studies on ventricular mechanics in pediatric pulmonary arterial hypertensionRV ejection fraction (RVEF) and RV systolic pressure (RVSP) are comparable between pulmonary artery hypertension (PAH) patients and PAB mice. a RVEF is reduced in PAH subjects (57 ± 6% in PAH versus 44 ± 9% in controls, p < 0.001) and PAB mice (62 ± 7% in PAB versus 37 ± 11% in Sham, p < 0.001) compared to control (CTRL) subjects and Sham mice, b RVSP is significantly increased in both PAH patients (63 ± 23 mmHg, p < 0.001) versus known healthy values [55], and PAB mice (64 ± 16 mmHg, p < 0.001) relative to Sham mice (19 ± 1 mmHg). Note, RVSP was not measured for control subjects. Variables were compared between control and hypertensive groups using a Student’s unpaired t-test with an α = 0.05. Data is expressed as mean ± SD. n = 18 in PAH cohort; n = 17 in control cohort; n = 12 in PAB group; n = 9 in Sham groupBack to article page