Fig. 4

Principle component analysis (PCA) of 22 metrics of myocardial strain reveals distinct clusters based on disease status, with PAB mice (▲, red), Sham mice (▲, blue), PAH patients (●, red), and control subjects (●, blue); a PC1 versus PC2, and b PC1 versus PC3. n = 18 in PAH cohort; n = 17 in control cohort; n = 12 in PAB group; n = 9 in Sham group. The variable weights correspond to the strain parameters listed on the right