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Table 1 Patient demographics and hemodynamic characteristics

From: Pulmonary arterial banding in mice may be a suitable model for studies on ventricular mechanics in pediatric pulmonary arterial hypertension

Parameter

PAH (n = 18)

Control (n = 17)

p-value

Female, n (%)

12 (66%)

11 (65%)

0.93

Age, y

13 (9–20)

10 (7–16)

0.08

Body surface area, m2

1.53 (0.83–1.76)

1.43 (0.98–1.77)

0.83

Height, cm

153.8 (123.7–163.1)

150.2 (127.4–176.1)

0.52

Weight, kg

50.8 (20.6–67.8)

46.6 (26.4–90.6)

0.98

WHO class I

18 (100%)

…

…

PVR (Pa s/m3)

8.5 (2.3–22.8)

…

…

mPAP, mmHg

49 (24–58)

…

…

PCWP (mmHg)

9 (5–12)

…

…

LVEF (%)

57 (42–65)

59 (53–66)

0.32

RVEF (%)

45 (22–54)

58 (47–67)

< 0.001

RV CO (mL/min)

5.6 (2.2–11.3)a

4.5 (2.5–8.4)

0.96

RV SV (mL)

76.2 (26.7–106.8)

63.4 (35.8–97.1)

0.15

  1. Data are expressed as median values (interquartile range), n (%), unless otherwise noted
  2. Bold p-values represent significance
  3. PAH pulmonary artery hypertension, WHO World Health Organization, PVR pulmonary vascular resistance, mPAP mean pulmonary arterial pressure, PCWP pulmonary capillary wedge pressure, LVEF left ventricular ejection fraction, RV right ventricle, RVEF right ventricular ejection fraction, CO cardiac output, SV stroke volume
  4. aIndicates non-normally distributed values tested with the Mann–Whitney test