Skip to main content

Table 2 Multivariable models inclusive of baseline characteristics and RVI fibrosis for the primary outcome

From: Right ventricular insertion site fibrosis in a dilated cardiomyopathy referral population: phenotypic associations and value for the prediction of heart failure admission or death

Characteristics

Univariable

Model 1a

Model 2b

Model 3c

 

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

Demographics

            

 Age

1.02

1.002–1.03

0.03

         

 Systolic blood pressure

0.99

0.98–0.997

0.01

         

 Heart rate

1.02

1.007–1.03

0.001

1.02

1.004–1.03

0.01

1.02

1.003–1.03

0.01

   

 Hypertension

1.41

0.99–1.99

0.06

         

 Diabetes

2.33

1.62–3.37

< 0.001

2.32

1.57–3.43

< 0.001

   

1.97

1.32–2.94

0.001

 Hyperlipidemia

1.74

1.21–2.51

0.003

         

 NYHA 3–4

1.81

1.23–2.66

0.002

         

Medications

 ACEi/ARB

2.41

1.33–4.36

0.004

         

 Beta blocker

2.20

1.21–3.98

0.009

         

 Diuretics

3.28

2.2–4.90

< 0.001

   

2.18

1.37–3.47

0.001

1.84

1.14–2.96

0.01

CMR variables

 LVEF

0.95

0.94–0.97

< 0.001

0.97

0.95–0.98

< 0.001

0.98

0.96–0.995

0.01

0.97

0.95–0.99

0.001

 RVEF

0.97

0.95–0.98

< 0.001

         

 LA volume index

1.02

1.01–1.02

< 0.001

         

RVI fibrosis

2.11

1.48–2.99

< 0.001

1.75

1.18–2.60

0.01

1.66

1.12–2.46

0.01

1.61

1.09–2.40

0.02

  1. ACEi Angiotensin-converting enzyme inhibitors, ARB Angiotensin II receptor blocker, BP blood pressure, EF ejection fraction, LA left atrial, LV left ventricular, NYHA New York Heart Association, RV right ventricular, RVI right ventricular insertion point
  2. aModel 1 represents multivariable Cox regression model with age, systolic BP, Heart rate, Hypertension, Diabetes, Hyperlipidemia, NYHA 3–4, LVEF, RVEF, indexed LA volume, RVI fibrosis (present or absent)
  3. bModel 2 represents multivariable Cox regression model with age, systolic BP, Heart rate, NYHA 3–4, ACEi/ARB, Beta Blocker, Diuretics, LVEF, RVEF, indexed LA volume, RVI fibrosis (present or absent)
  4. cModel 3 represents represents multivariable Cox regression model with age, Hypertension, Diabetes, NYHA 3–4, ACEi/ARB, Beta Blocker, Diuretics, LVEF, RVEF, indexed LA volume, RVI fibrosis (present or absent)
Back to article page

Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

Contact us