| Group 0 Control (n = 5) | Group 1 2-week (n = 6) | Group 2 4-week (n = 8) | Group 3 6-week (n = 7) | Group 4 8-week (n = 7) | Group 5 12-week (n = 7) |
---|---|---|---|---|---|---|
Hct (%) | 58.8 ± 2.0 | 41.6 ± 13.0 | 46.3 ± 10.0 | 40.5 ± 12.0 | 43.9 ± 12.0 | 43.0 ± 14.0 |
Heart rate (min) | 281 ± 30 | 270 ± 24 | 280 ± 35 | 271 ± 28 | 279 ± 51 | 292 ± 51 |
LVEDV (ml) | 0.69 ± 0.05 | 0.73 ± 0.09 | 0.68 ± 0.09 | 0.77 ± 0.05 | 0.69 ± 0.09 | 0.63 ± 0.01 |
LVESV (ml) | 0.18 ± 0.02 | 0.20 ± 0.04 | 0.23 ± 0.03 | 0.27 ± 0.04 | 0.24 ± 0.06 | 0.26 ± 0.07 |
LVSV (ml) | 0.51 ± 0.06 | 0.52 ± 0.06 | 0.46 ± 0.10 | 0.50 ± 0.05 | 0.45 ± 0.07 | 0.37 ± 0.10 |
CO (l/min) | 0.15 ± 0.01 | 0.14 ± 0.01 | 0.13 ± 0.03 | 0.14 ± 0.03 | 0.13 ± 0.03 | 0.10 ± 0.03* |
LV mass (g) | 0.66 ± 0.08 | 0.69 ± 0.09 | 0.67 ± 0.14 | 0.74 ± 0.11 | 0.64 ± 0.08 | 0.61 ± 0.06 |
LVEF(%) | 73 ± 4 | 72 ± 3 | 66 ± 8 | 65 ± 5 | 65 ± 7 | 59 ± 9* |
Native T1 (ms) | 1148 ± 58 | 1191 ± 119 | 1278 ± 49 | 1320 ± 56* | 1327 ± 82* | 1316 ± 69* |
T2 (ms) | 10.3 ± 1 | 12.2 ± 1 | 11.4 ± 1 | 16.3 ± 2* | 17.3 ± 5 | 14.0 ± 2 |
Partition coefficient | 0.36 | 0.28 | 0.32 | 0.35 | 0.38 | 0.43†|
ECV (%) | 14.3 ± 1 | 15.7 ± 1 | 17.1 ± 2 | 20.3 ± 3* | 21.2 ± 4* | 23.2 ± 4* |