Blood flow dynamics with four-dimensional flow cardiovascular magnetic resonance in patients with aortic stenosis before and after transcatheter aortic valve replacement

Table 2 Changes on hemodynamic and echocardiographic parameters before and after TAVR (n = 32)

Variables	Pre-TAVR	Post-TAVR	P value
Heart rate (bpm)	66 (61–76.5)	70.5 (61–79.5)	0.67
Systolic blood pressure (mmHg)	120 (110–127)	118 (110–129.5)	0.33
Diastolic blood pressure (mmHg)	64.5 (57.5–68.5)	60.5 (48.5–71.5)	0.40
Peak aortic velocity (V_max) (m/s)	4.6 ± 0.8	2.3 ± 0.4	< 0.001
Mean transaortic PG (m/s)	53 ± 21	12 ± 4	< 0.001
AVAI or EOAI (cm²/m²)	0.5 ± 0.1	1.1 ± 0.2	< 0.001
Paravalvular leak severity I/II/III/IV, n (%)	–	24 (75)/4 (13)/0/0	–
LVEDD (mm)	46.7 (43.0–50.0)	46.0 (42.5–49.0)	0.99
LVESD (mm)	28.0 (24.5–34.5)	28.5 (25.0–32.0)	0.71
LVEF (%)	61 (54–70)	64 (56–70)	0.010
Transmitral peak E/A ratio	0.70 (0.56–0.97)	0.70 (0.62–0.91)	0.058
E/e′ ratio	13.1 ± 4.8	14.0 ± 4.2	0.25
LAVI (mL/m²)	45.5 (39.7–63.0)	44.8 (36.1–58.5)	0.78
LVMI (g/m²)	118 (102–141)	115 (98–145)	0.65
RWT	0.44 (0.39–0.49)	0.44 (0.38–0.47)	0.63

Continuous variables are presented as mean ± standard deviation if normally distributed, and median (interquartile range) if not normally distributed
Categorical variables are presented as number of patients (%)
AVAI aortic valve area index; EOAI effective orifice area index; LAVI left atrial volume index; LVEDD left ventricular end-diastolic dimension; LVESD left ventricular end-systolic dimension; LVEF left ventricular ejection fraction; LVMI left ventricular mass index; PG pressure gradient; RWT relative wall thickness; TAVR transcatheter aortic valve replacement

ISSN: 1532-429X