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Table 2 Cox proportional hazards of strain and tissue properties associated with a composite outcome of heart failure hospitalization and all-cause mortality

From: The association of reduced left ventricular strains with increased extracellular volume and their collective impact on clinical outcomes

Primary parameter

 

HR

LL

UL

 

HRADJa

LL

UL

GLS ≥ − 11.0%

 

2.49

1.27

4.89

 

2.44

1.18

5.06

GCS ≥ − 11.4%

 

2.38

1.29

4.40

 

2.13

1.09

4.16

GRS ≤ 15.7%

 

2.34

1.26

4.33

 

2.23

1.16

4.27

ECV ≥ 28.3%

 

3.21

1.71

6.01

 

3.18

1.52

6.66

Native T1 ≥ 992 ms

 

1.62

0.88

2.99

 

1.51

0.78

2.94

Post-contrast T1 < 470 ms

 

2.25

1.21

4.21

 

2.02

1.01

4.03

Hierarchical GLS and ECV model

        

GLS < − 11.0%, ECV < 28.3%

 

1.00

(Reference)

 

1.00

(Reference)

GLS ≥ − 11.0%, ECV < 28.3%

 

2.41

0.89

6.52

 

2.24

0.82

6.12

GLS < − 11.0%, ECV ≥ 28.3%

 

3.65

1.18

11.32

 

3.05

0.87

10.64

GLS ≥ − 11.0%, ECV ≥ 28.3%

 

6.34

2.51

16.00

 

6.01

2.19

16.53

  1. CI confidence interval, GLS global longitudinal strain, GCS global circumferential strain, GRS global radial strain, ECV extracellular volume, HRADJ  adjusted hazard ratio
  2. aAdjusted for age, gender, hypertension, diabetes, and infarct pattern on late gadolinium enhancement imaging