Table 3 Clinical characteristics of Fontan patients with and those without the composite outcome
|  | Composite outcome N = 22 | No composite outcome N = 33 | P value |
|---|---|---|---|
Demographics | |||
 Gender (male) | 11 (50%) | 21 (64%) | 0.315 |
 Median age (years) | 10 (4–16) | 14 (5–18) | 0.35 |
 DLV | 11 (50%) | 24 (73%) | 0.086 |
Surgical data | |||
 Median age at BCPC (months) | 5 (2–8) | 6 (2–12) | 0.26 |
 Median age at Fontan (months) | 37 (29–61) | 40 (18–56) | 0.52 |
 Cumulative bypass time (min) | 252 ± 129 | 213 ± 117 | 0.256 |
 Cumulative cross clamp time (min) | 81 ± 59 | 48 ± 61 | 0.055 |
 Cumulative DHCA time (min) | 10 ± 14 | 3 ± 10 | 0.063 |
Clinical information | |||
 Height (cm) | 136 (100–183) | 154 (99–180) | 0.54 |
 Weight (kg) | 33 (15–62) | 47 (21–146) | 0.56 |
 Heart rate (bpm) | 85 (61–145) | 78 (57–105) | 0.025 |
 Saturations (%) | 94 (78–98) | 95 (91–98) | 0.87 |
 Systolic BP percentile | 68 (13–100) | 63 (3–100) | 0.82 |
 Diastolic BP percentile | 40 (11–100) | 37 (8–99) | 0.31 |
 Hematocrit | 0.44 ± 0.04 | 0.45 ± 0.04 | 0.964 |
Cardiac catheterization | |||
 Median interval cath to MRI (days) | 0 (0–206) | 0 (0–103) | 0.617 |
 SVEDP (mmHg) | 7 ± 3 | 9 ± 3 | 0.232 |
 CVP (mmHg) | 10 ± 1 | 11 ± 2 | 0.406 |
 MAP (mmHg) | 5 ± 1 | 7 ± 4 | 0.256 |
Echocardiography | |||
 Median interval CMR to echo (days) | 52 (6–226) | 124 (2–351) | 0.57 |
 Moderate to severe AVVR | 8 (36%) | 8 (24%) | 0.332 |
 Moderate to severe AR | 0 | 4 (12%) | 0.090 |
Cardiopulmonary exercise testing | |||
 Median interval CMR to CPET (days) | 27 (0–337) | 145 (0–343) | 0.97 |
 VO2 max (% predicted) | 78.2 ± 9.7 | 75.9 ± 16.8 | 0.70 |
 Work-load (% predicted) | 77.1 ± 17.2 | 85.1 ± 14.1 | 0.211 |
 Anaerobic threshold (% predicted) | 77.2 ± 16.4 | 77.1 ± 16.4 | 0.104 |