Skip to main content

Table 2 Multiparametric TTE classification of MR: TTE, standard, and 4D flow CMR values

From: Quantification of regurgitation in mitral valve prolapse with four-dimensional flow cardiovascular magnetic resonance

  Control (6) MR group (54) MR Grade 1 + /2 + (12) MR Grade 3 + (12) MR Grade 4 + (30)
Echocardiographic parameters     
LVEDV, ml 133 ± 28 175 ± 67 133 ± 44@ 140 ± 37@ 206 ± 69
LVESV, ml 48 ± 9 58 ± 28 52 ± 21 44 ± 13 67 ± 33
LVEF, % 64 ± 4 67 ± 7 61 ± 6#@ 68 ± 6 68 ± 6
LVOT SV, ml 80 ± 2 71 ± 16 73 ± 14 80 ± 13 67 ± 17
EROA, cm2 * n.a 0.49 ± 0.28 0.16 ± 0.13#@ 0.36 ± 0.09@ 0.68 ± 0.22
RVol, ml * n.a 73 ± 39 22 ± 16#@ 54 ± 8@ 101 ± 25
RF, % * n.a 47 ± 18 21 ± 10#@ 40 ± 4@ 60 ± 8
Vena contracta, cm n.a 0.62 ± 0.29 0.29 ± 0.15#@ 0.60 ± 0.09@ 0.76 ± 0.09
E wave, m/s 0.77 ± 0.21 1.36 ± 0.38§ 0.92 ± 0.19#@ 1.22 ± 0.16@ 1.58 ± 0.31
PW Doppler parameters     
MV SV, ml 84 ± 3 139 ± 42§ 96 ± 27#@ 124 ± 16@ 163 ± 38
RVol, ml 3 ± 3 69 ± 42§ 22 ± 17#@ 48 ± 13@ 96 ± 36
RF, % 4 ± 3 45 ± 18§ 21 ± 12#@ 38 ± 7@ 58 ± 11
CMR parameters     
LVEDV, ml 169 ± 24 220 ± 71§ 172 ± 50@ 186 ± 45@ 254 ± 70
LVESV, ml 66 ± 12 85 ± 38§ 70 ± 36 68 ± 25 98 ± 39
LV SV, ml 103 ± 14 135 ± 38§ 102 ± 24@ 117 ± 23@ 156 ± 35
LVEF, % 63 ± 5 62 ± 7 61 ± 10 64 ± 7 62 ± 6
Aorta forward flow, ml 98 ± 12 78 ± 21§ 82 ± 19 80 ± 16 76 ± 23
Aorta net flow (SV), ml 97 ± 11 74 ± 19§ 77 ± 19 74 ± 12 72 ± 22
RVol, ml 5 ± 4 57 ± 34§ 21 ± 16#@ 37 ± 11@ 80 ± 26
RF, % 4 ± 3 41 ± 17§ 20 ± 13#@ 33 ± 7@ 53 ± 11
4D flow CMR (indirect)     
MV SV, ml 93 ± 16 124 ± 39 99 ± 25@ 119 ± 23 135 ± 44
LVOT net flow (SV), ml 86 ± 15 68 ± 16§ 73 ± 13 77 ± 9@ 62 ± 17
RVol, ml ** 7 ± 6 56 ± 35§ 26 ± 16#@ 43 ± 16@ 73 ± 36
RF, % ** 7 ± 6 42 ± 16§ 24 ± 11#@ 35 ± 6@ 52 ± 13
4D flow CMR (direct)     
RVol, ml *** n.a 51 ± 25 28 ± 12@ 43 ± 15 59 ± 25
RF, % *** n.a 40 ± 16 25 ± 9@ 35 ± 9 46 ± 16
  1. TTE transthoracic echocardiography, MR mitral valve regurgitation, CMR cardiac magnetic resonance, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVEF left ventricular ejection fraction, LVOT left ventricular outflow tract, SV stroke volume, EROA effective regurgitant orifice area, RVol regurgitant volume (MR), RF regurgitant fraction (MR), PW pulse-wave, MV mitral valve. Values are expressed as mean ± SD. *2D-PISA method (n = 54). **4D flow indirect (n = 60) and ***direct (n = 46) method. Differences reached statistical significance with: § control, # group “MR grade 3 + ”, and @ group “MR grade 4 + ”