Prognostic value of vasodilator stress perfusion cardiovascular magnetic resonance after inconclusive stress testing

Table 4 Discrimination associated with the CMR-parameters for the prediction of MACE

	MACE
	C-index (95%CI)	Global χ² statistic	LR-test
Model 1^a (stepwise selection)	0.63 (0.60–0.68)	420.1	Reference
Model 2a^b (model 1 + presence of ischemia)	0.73 (0.66–0.79)	580.9	< 0.001
Model 2b^c (model 1 + number of ischemic segments)	0.75 (0.69–0.81)	607.4	< 0.001
Model 2c^d (model 1 + ischemia with or without CMR-related revascularization)	0.73 (0.66–0.80)	570.2	< 0.001

BMI body mass index, CAD coronary artery disease, CI confidence interval, CV cardiovascular, HF heart failure, LGE late gadolinium enhancement, LVEF left ventricular ejection fraction, MACE major adverse cardiac events
^aCovariates in the model 1 by stepwise variable selection with entry and exit criteria set at the p ≤ 0.1 level: age, male, hypertension, diabetes, dyslipidemia, known CAD, LVEF per 10% and presence of LGE
^bCovariates in the model 2a: model 1 with presence of ischemia
^cCovariates in the model 2b: model 1 with number of ischemic segments
^dCovariates in the model 2c: model 1 with presence of ischemia with or without CMR-related coronary revascularization. This variable was defined in three categories: presence of ischemia without CMR-related coronary revascularization, presence of ischemia with CMR-related coronary revascularization and absence of ischemia (reference for hazard ratio calculations)

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