| |
All patients N = 1212
|
Patients with known CAD N = 693
|
Patients with suspected CAD N = 519
|
*P-value
|
|---|
|
Clinical variables
|
|
Age, years
|
69 ± 10
|
69 ± 10
|
68 ± 11
|
0.37
|
|
Male
|
921 (76%)
|
554 (80%)
|
367 (71%)
|
< 0.005
|
|
BMI, kg/m2
|
24 ± 3
|
24 ± 3
|
24 ± 4
|
0.49
|
|
Hypertension
|
823 (68%)
|
483 (70%)
|
340 (66%)
|
0.13
|
|
Dyslipidemia
|
821 (68%)
|
488 (70%)
|
333 (64%)
|
0.021
|
|
Diabetes mellitus
|
366 (30%)
|
229 (33%)
|
137 (26%)
|
0.012
|
|
Current smoking
|
79 (7%)
|
55 (8%)
|
24 (5%)
|
0.021
|
|
Blood test
|
|
HbA1c, %
|
6.0 ± 0.8
|
6.1 ± 0.9
|
5.9 ± 0.7
|
0.005
|
|
LDL cholesterol
|
99 ± 28
|
94 ± 27
|
107 ± 30
|
< 0.001
|
|
eGFR
|
66 ± 16
|
67 ± 16
|
66 ± 15
|
0.42
|
|
CMR variables
|
|
LVEDV, mL
|
131 ± 46
|
128 ± 42
|
134 ± 51
|
0.053
|
|
LVESV, mL
|
57 ± 37
|
55 ± 33
|
59 ± 42
|
0.24
|
|
LV mass, g
|
95 ± 34
|
92 ± 36
|
99 ± 31
|
< 0.001
|
|
LVEF, %
|
60 ± 12
|
60 ± 12
|
59 ± 12
|
0.84
|
|
Presence of LGE
|
591 (49%)
|
439 (63%)
|
152 (29%)
|
< 0.001
|
|
LGE, %
|
7.9 ± 9.0
|
9.6 ± 9.6
|
5.9 ± 7.7
|
< 0.001
|
|
Presence of ischemia
|
516 (43%)
|
195 (28%)
|
321 (62%)
|
0.002
|
|
> 10% ischemia
|
258 (21%)
|
175 (25%)
|
83 (16%)
|
< 0.001
|
- Data are expressed as mean ± SD or number (%)
- *P-value represents significance of difference between patients with known CAD and suspected CAD
- BMI body mass index, CAD coronary artery disease, CFR coronary flow reserve, CMR cardiac magnetic resonance, eGFR estimated glomerular filtration rate, LDL low-density lipoprotein, LGE late gadolinium enhancement, LV left ventricular, LVEDV left ventricular end-diastolic volume, LVEF left ventricular ejection fraction, LVESV left ventricular end-systolic volume, MACE major adverse cardiac events
