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Table 2 Comparison of CMR parameters between HFpEF with events and those without

From: Cardiovascular magnetic resonance assessment of coronary flow reserve improves risk stratification in heart failure with preserved ejection fraction

 

All HFpEF

(n = 163)

HFpEF with events

(n = 26)

HFpEF without events

(n = 137)

P-value*

LV ejection fraction, %

64.4 ± 7.3

62.0 ± 8.2

64.9 ± 7.0

0.29

LVEDVI, ml/m2

71.5 ± 17.2

72.8 ± 26.8

71.2 ± 14.7

0.66

LVESVI, ml/m2

25.8 ± 9.6

28.7 ± 14.7

25.3 ± 8.2

0.10

LV mass index, g/m2

88.0 ± 28.9

97.3 ± 27.9

86.2 ± 28.8

0.072

RV ejection fraction, %

44.8 ± 2.7

44.4 ± 2.6

44.9 ± 2.7

0.33

Presence of LGE, n (%)

74 (45%)

17 (65%)

57 (42%)

0.026

%LGE, %

5.7 ± 7.0

9.2 ± 7.7

5.0 ± 6.6

0.004

Ischemia on perfusion CMR

0 (0%)

0 (0%)

0 (0%)

–

Global radial strain, %

49.7 ± 11.8

47.0 ± 11.7

50.2 ± 11.8

0.21

Global circumferential strain, %

− 15.3 ± 3.1

− 13.0 ± 2.4

− 15.8 ± 3.0

 < 0.001

Global longitudinal strain, %

− 17.4 ± 3.0

− 15.8 ± 2.4

− 17.8 ± 3.0

0.002

RV longitudinal strain, %

− 17.7 ± 3.3

− 15.5 ± 2.5

− 18.1 ± 3.3

 < 0.001

Myocardial blood flow at rest, ml/min/g

1.03 ± 0.19

1.03 ± 0.19

1.06 ± 0.21

0.30

Myocardial blood flow during ATP infusion, ml/min/g

2.61 ± 0.67

2.02 ± 0.50

2.72 ± 0.64

0.15

Coronary flow reserve

2.55 ± 0.57

1.93 ± 0.38

2.67 ± 0.52

 < 0.001

Coronary flow reserve < 2.0, n (%)

15 (9%)

11 (42%)

4 (3%)

 < 0.001

  1. Data are presented as mean ± standard deviation or number (%)
  2. *Indicates statistical significance in the differences between HFpEF patients with events and those without
  3. ATP adenosine triphosphate, HFpEF heart failure with preserved ejection fraction, LGE late gadolinium enhancement, LV left ventricular, LVEDVI left ventricular end-diastolic volume index, LVESVI left ventricular end-systolic volume index, RV right ventricular