| All HFpEF (n = 163) | HFpEF with events (n = 26) | HFpEF without events (n = 137) | P-value* |
---|---|---|---|---|
LV ejection fraction, % | 64.4 ± 7.3 | 62.0 ± 8.2 | 64.9 ± 7.0 | 0.29 |
LVEDVI, ml/m2 | 71.5 ± 17.2 | 72.8 ± 26.8 | 71.2 ± 14.7 | 0.66 |
LVESVI, ml/m2 | 25.8 ± 9.6 | 28.7 ± 14.7 | 25.3 ± 8.2 | 0.10 |
LV mass index, g/m2 | 88.0 ± 28.9 | 97.3 ± 27.9 | 86.2 ± 28.8 | 0.072 |
RV ejection fraction, % | 44.8 ± 2.7 | 44.4 ± 2.6 | 44.9 ± 2.7 | 0.33 |
Presence of LGE, n (%) | 74 (45%) | 17 (65%) | 57 (42%) | 0.026 |
%LGE, % | 5.7 ± 7.0 | 9.2 ± 7.7 | 5.0 ± 6.6 | 0.004 |
Ischemia on perfusion CMR | 0 (0%) | 0 (0%) | 0 (0%) | – |
Global radial strain, % | 49.7 ± 11.8 | 47.0 ± 11.7 | 50.2 ± 11.8 | 0.21 |
Global circumferential strain, % | − 15.3 ± 3.1 | − 13.0 ± 2.4 | − 15.8 ± 3.0 |  < 0.001 |
Global longitudinal strain, % | − 17.4 ± 3.0 | − 15.8 ± 2.4 | − 17.8 ± 3.0 | 0.002 |
RV longitudinal strain, % | − 17.7 ± 3.3 | − 15.5 ± 2.5 | − 18.1 ± 3.3 |  < 0.001 |
Myocardial blood flow at rest, ml/min/g | 1.03 ± 0.19 | 1.03 ± 0.19 | 1.06 ± 0.21 | 0.30 |
Myocardial blood flow during ATP infusion, ml/min/g | 2.61 ± 0.67 | 2.02 ± 0.50 | 2.72 ± 0.64 | 0.15 |
Coronary flow reserve | 2.55 ± 0.57 | 1.93 ± 0.38 | 2.67 ± 0.52 |  < 0.001 |
Coronary flow reserve < 2.0, n (%) | 15 (9%) | 11 (42%) | 4 (3%) |  < 0.001 |