Fig. 1

a MV point annotation illustration at end-diastole and end-systole in 2-chamber view, with anterior and inferior points, and 4-chamber view, with lateral and septal points, and b the clinical-metric derivation as an output of the time-resolved annotation. The MV displacement was measured as the average of the perpendicular distances from the MV initial plane, defined at end-diastole in each view, to every MV point at every temporal frame, and the MV velocity was measured as its time-derivative. MAPSE was calculated as the maximum displacement, and LV s’, e’ and a’ as the first, second and third global velocity peak. MV mitral valve, MAPSE mitral annular plane systolic excursion, LV left ventricle