Table 3 Comparison of DCM patients without and with a primary endpoint

Age [years]

51.6 ± 15.2

55.2 ± 15.3

0.10

Male gender [n]

214 (73.5%)

45 (76.3%)

0.66

Weight [kg]

80.5 ± 16.0

76.4 ± 14.0

0.07

Height [cm]

176.0 ± 8.9

174.8 ± 11.1

0.44

BMI [kg/m²]

25.9 ± 4.4

24.9 ± 3.4

< 0.05

Heart rate [1/min]

70.8 ± 15.2

74.4 ± 15.0

0.09

Atrial fibrillation [n]

46 (15.8%)

11 (18.6%)

0.58

NYHA class [n]

 I

72 (24.7%)

12 (20.3%)

0.50

 II

133 (45.7%)

19 (32.2%)

0.08

 III

80 (27.5%)

28 (47.5%)

< 0.01

 IV

6 (2.1%)

0

–

Cardiovascular risk factors [n]

 Arterial hypertension

127 (43.6%)

27 (45.8%)

0.75

 Dyslipidemia

76 (26.1%)

13 (22.0%)

0.51

 Diabetes

31 (10.7%)

11 (18.6%)

0.14

 Smoker

119 (40.9%)

21 (35.6%)

0.50

 Family history of CAD

63 (21.6%)

14 (23.7%)

0.66

 Obesity

47 (16.2%)

5 (8.5%)

0.08

Heart failure therapy [n]

 ACE inhibitor/ARB

287 (98.6%)

59 (100.0%)

0.57

 ß-Blocker

245 (84.2%)

54 (91.5%)

0.11

 Aldosterone receptor antagonist

112 (38.5%)

34 (57.6%)

< 0.01

 Loop diuretic

128 (44.0%)

42 (71.2%)

< 0.001

Laboratory findings

 Creatinine [mg/dl]

0.9 (0.8–1.1)

1.1 (0.9–1.3)

0.45

 NT-pro BNP [ng/l]^†

275.0 (102.3–1229.8)

1831 (411.3–4976.3)

< 0.05

CMR parameters

 LVEF [%]

38.2 ± 13.2

27.1 ± 12.7

< 0.001

 LVEDV [ml]

239 ± 81

298 ± 133

< 0.01

 LV mass [g]

139 ± 50

189 ± 205

0.07

 Presence of LGE [n]

97 (33.3%)

37 (62.7%)

< 0.001

 GLS [%]

− 10.3 ± 4.5

− 7.5 ± 3.7

< 0.001

 GCS [%]

− 10.0 ± 4.9

− 6.6 ± 3.6

< 0.001

 GRS [%]

24.7 ± 12.2

17.7 ± 9.4

< 0.001

 Apical rotation [°]

1.9 ± 4.2

2.3 ± 3.9

0.36

 Basal rotation [°]

− 2.5 ± 3.7

− 2.3 ± 3.0

0.84

 LV twist [°]

5.6 ± 3.1

5.0 ± 2.5

0.11

 LV torsion [°/cm]

1.2 ± 0.7

1.0 ± 0.6

< 0.05

 Normal directed rotation [n]

159 (54.6%)

32 (54.2%)

0.98

 Reversed apical rotation [n]

89 (27.1%)

15 (25.4%)

0.84